4QMO
MST3 IN COMPLEX WITH Imidazolo-oxindole PKR inhibitor C16
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 401 |
| Chain | Residue |
| A | LYS245 |
| A | PRO246 |
| A | ASN256 |
| A | LYS272 |
| A | ARG276 |
| A | HOH632 |
| A | HOH710 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 34L A 402 |
| Chain | Residue |
| A | ALA51 |
| A | MET99 |
| A | GLU100 |
| A | TYR101 |
| A | LEU102 |
| A | LEU151 |
| A | HOH577 |
| A | HOH667 |
| A | ILE30 |
| A | LYS32 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PG4 A 403 |
| Chain | Residue |
| A | PRO218 |
| A | HIS219 |
| A | ASN234 |
| A | ASN235 |
| A | PRO236 |
| A | PRO237 |
| A | THR238 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE DMS A 404 |
| Chain | Residue |
| A | MET13 |
| A | GLN14 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 405 |
| Chain | Residue |
| A | GLY103 |
| A | GLU154 |
| A | HOH608 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGKGSFGEVFkGidnrtqkv..........VAIK |
| Chain | Residue | Details |
| A | ILE30-LYS53 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | Motif: {"description":"Bipartite nuclear localization signal"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 13 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine; by autocatalysis","evidences":[{"source":"PubMed","id":"17046825","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19604147","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20124694","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
