Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| C | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| D | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| D | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 B 101 |
| Chain | Residue |
| A | MET36 |
| A | ASN37 |
| A | HOH131 |
| A | HOH154 |
| B | GLY40 |
| C | THR4 |
| C | HOH129 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 102 |
| Chain | Residue |
| B | ARG8 |
| B | HOH257 |
| A | HOH136 |
| B | LYS7 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 D 101 |
| Chain | Residue |
| C | ARG87 |
| C | HOH146 |
| D | LYS7 |
| D | ARG8 |
| D | HOH224 |
| D | HOH252 |
| D | HOH253 |
| site_id | AC4 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR CHAIN F OF P1-P6 PEPTIDE |
| Chain | Residue |
| A | ARG8 |
| A | LEU23 |
| A | ASN25 |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| A | ASP30 |
| A | ILE47 |
| A | GLY48 |
| A | GLY49 |
| A | VAL82 |
| A | HOH106 |
| A | HOH140 |
| B | ARG8 |
| B | LEU23 |
| B | ASN25 |
| B | GLY27 |
| B | ALA28 |
| B | ASP29 |
| B | ASP30 |
| B | LYS45 |
| B | ILE47 |
| B | GLY48 |
| B | GLY49 |
| B | VAL50 |
| B | VAL82 |
| B | HOH202 |
| B | HOH253 |
| F | HOH104 |
| F | HOH105 |
| site_id | AC5 |
| Number of Residues | 38 |
| Details | BINDING SITE FOR CHAIN G OF P1-P6 PEPTIDE |
| Chain | Residue |
| A | ASN88 |
| A | THR91 |
| A | GLN92 |
| B | TRP6 |
| C | ARG8 |
| C | LEU23 |
| C | ASN25 |
| C | GLY27 |
| C | ALA28 |
| C | ASP29 |
| C | VAL32 |
| C | GLY48 |
| C | GLY49 |
| C | PHE53 |
| C | ILE84 |
| C | HOH113 |
| C | HOH132 |
| D | ARG8 |
| D | LEU23 |
| D | ASN25 |
| D | GLY27 |
| D | ALA28 |
| D | ASP29 |
| D | ASP30 |
| D | LYS45 |
| D | MET46 |
| D | ILE47 |
| D | GLY48 |
| D | GLY49 |
| D | VAL50 |
| D | VAL82 |
| D | HOH204 |
| G | HOH101 |
| G | HOH103 |
| G | HOH104 |
| G | HOH105 |
| G | HOH108 |
| G | HOH109 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 276 |
| Details | Domain: {"description":"Peptidase A2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00275","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 40 |
| Details | Region: {"description":"Dimerization of protease","evidences":[{"source":"UniProtKB","id":"P04585","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Active site: {"description":"For protease activity; shared with dimeric partner","evidences":[{"source":"PROSITE-ProRule","id":"PRU10094","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Site: {"description":"Cleavage; by viral protease","evidences":[{"evidenceCode":"ECO:0000250"}]} |
