4QI1

Crystal structure of H. walsbyi bacteriorhodopsin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005216	molecular_function	monoatomic ion channel activity
A	0005886	cellular_component	plasma membrane
A	0006811	biological_process	monoatomic ion transport
A	0007602	biological_process	phototransduction
A	0009881	molecular_function	photoreceptor activity
A	0016020	cellular_component	membrane
A	1902600	biological_process	proton transmembrane transport
B	0005216	molecular_function	monoatomic ion channel activity
B	0005886	cellular_component	plasma membrane
B	0006811	biological_process	monoatomic ion transport
B	0007602	biological_process	phototransduction
B	0009881	molecular_function	photoreceptor activity
B	0016020	cellular_component	membrane
B	1902600	biological_process	proton transmembrane transport
C	0005216	molecular_function	monoatomic ion channel activity
C	0005886	cellular_component	plasma membrane
C	0006811	biological_process	monoatomic ion transport
C	0007602	biological_process	phototransduction
C	0009881	molecular_function	photoreceptor activity
C	0016020	cellular_component	membrane
C	1902600	biological_process	proton transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE RET A 301

Chain	Residue
A	TRP94
A	THR97
A	THR98
A	LEU101
A	SER149
A	THR150
A	TRP190
A	TYR193
A	LYS224

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MPG A 302

Chain	Residue
A	PHE96
A	LEU103
A	ILE116
A	ALA124
A	MPG304
C	PHE96

---

site_id	AC3
Number of Residues	12
Details	BINDING SITE FOR RESIDUE MPG A 303

Chain	Residue
A	MET31
A	ILE35
A	GLY38
A	LEU39
A	LYS47
A	ILE54
A	ALA58
A	ALA61
B	ILE122
B	PHE125
B	SER152
B	TYR159

---

site_id	AC4
Number of Residues	16
Details	BINDING SITE FOR RESIDUE MPG A 304

Chain	Residue
A	ARG114
A	ASP115
A	GLY117
A	ALA118
A	GLY121
A	ALA124
A	VAL128
A	MPG302
C	LYS47
C	GLU48
C	VAL51
C	ILE52
C	LEU55
C	ILE59
C	MPG302
C	HOH482

---

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL A 305

Chain	Residue
A	GLU14
A	TYR210
B	VAL83

---

site_id	AC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE RET B 301

Chain	Residue
B	TRP94
B	THR97
B	THR98
B	SER149
B	THR150
B	TRP190
B	TYR193
B	LYS224

---

site_id	AC7
Number of Residues	13
Details	BINDING SITE FOR RESIDUE MPG B 302

Chain	Residue
B	GLU48
B	LEU55
B	ILE59
B	ALA89
B	HOH447
B	HOH523
B	HOH595
C	ARG114
C	GLY117
C	GLY121
C	ALA124
C	VAL128
C	VAL132

---

site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MPG B 303

Chain	Residue
A	PHE96
A	HOH569
B	THR74
B	TRP88
B	LEU135
B	LYS137
C	HOH444

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MPG B 304

Chain	Residue
B	THR147
B	PHE155
B	TYR158
B	TYR159

---

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MPG B 305

Chain	Residue
B	LEU157
B	TYR158
B	VAL161
B	GLU166

---

site_id	BC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MPG B 306

Chain	Residue
B	THR24
B	MET31
B	GLY38
B	LEU39
B	ALA61
B	HOH591
C	ILE122
C	PHE125
C	TYR159

---

site_id	BC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE RET C 301

Chain	Residue
C	LYS224
C	TRP94
C	THR98
C	MET126
C	SER149
C	THR150
C	TRP190
C	TYR193
C	ASP220

---

site_id	BC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MPG C 302

Chain	Residue
A	MPG304
C	PHE96
C	PRO99
C	SER112
C	GLN113
C	ARG114
C	HOH505

---

Functional Information from PROSITE/UniProt

site_id	PS00327
Number of Residues	12
Details	BACTERIAL_OPSIN_RET Bacterial rhodopsins retinal binding site. FMVLDLvAKvGF

Chain	Residue	Details
A	PHE216-PHE227

---

site_id	PS00950
Number of Residues	13
Details	BACTERIAL_OPSIN_1 Bacterial rhodopsins signature 1. RYaDWlFTTPLLL

Chain	Residue	Details
A	ARG90-LEU102

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	420
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
A	GLU16-ALA36
B	TYR91-ALA111
B	ILE116-THR136
B	ALA144-PHE164
B	ILE185-ALA205
B	GLU212-LEU232
C	GLU16-ALA36
C	VAL51-PHE71
C	TYR91-ALA111
C	ILE116-THR136
C	ALA144-PHE164
A	VAL51-PHE71
C	ILE185-ALA205
C	GLU212-LEU232
A	TYR91-ALA111
A	ILE116-THR136
A	ALA144-PHE164
A	ILE185-ALA205
A	GLU212-LEU232
B	GLU16-ALA36
B	VAL51-PHE71

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	SITE: Primary proton acceptor => ECO:0000250

Chain	Residue	Details
A	ASP93
B	ASP93
C	ASP93

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	MOD_RES: Pyrrolidone carboxylic acid => ECO:0000250

Chain	Residue	Details
A	GLN7
B	GLN7
C	GLN7

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	MOD_RES: N6-(retinylidene)lysine => ECO:0000250

Chain	Residue	Details
A	LYS224
B	LYS224
C	LYS224

---