4QGS
Substrate and cofactor-free form of the Aldehyde Reductase YqhD from E. coli.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000302 | biological_process | response to reactive oxygen species |
| A | 0005829 | cellular_component | cytosol |
| A | 0008106 | molecular_function | alcohol dehydrogenase (NADP+) activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0018455 | molecular_function | alcohol dehydrogenase [NAD(P)+] activity |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047655 | molecular_function | allyl-alcohol dehydrogenase activity |
| A | 1990002 | molecular_function | methylglyoxal reductase (NADPH) (acetol producing) activity |
| A | 1990362 | molecular_function | butanol dehydrogenase (NAD+) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A 401 |
| Chain | Residue |
| A | ASP194 |
| A | HIS198 |
| A | HIS267 |
| A | HIS281 |
| A | HOH636 |
| A | HOH743 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 402 |
| Chain | Residue |
| A | ARG380 |
| A | ARG23 |
| A | ILE353 |
| A | PRO354 |
Functional Information from PROSITE/UniProt
| site_id | PS00060 |
| Number of Residues | 21 |
| Details | ADH_IRON_2 Iron-containing alcohol dehydrogenases signature 2. WaTHmlGHeLTAmhgLdHAqT |
| Chain | Residue | Details |
| A | TRP264-THR284 |
| site_id | PS00913 |
| Number of Residues | 29 |
| Details | ADH_IRON_1 Iron-containing alcohol dehydrogenases signature 1. AVlDpvytytlPprqvAnGvvDAFvhtvE |
| Chain | Residue | Details |
| A | ALA173-GLU201 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 11 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15327949","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OJ7","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15327949","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAY-2014","submissionDatabase":"PDB data bank","title":"Open form of E. coli YqhD.","authors":["LaMattina J.W.","Kapoor S.","Gouvea I.","Slovic A.","Lanzilotta W.N."]}},{"source":"PDB","id":"1OJ7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4QGS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
