4QEZ
Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Bacillus anthracis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0008782 | molecular_function | adenosylhomocysteine nucleosidase activity |
| A | 0008930 | molecular_function | methylthioadenosine nucleosidase activity |
| A | 0009116 | biological_process | nucleoside metabolic process |
| A | 0009164 | biological_process | nucleoside catabolic process |
| A | 0019284 | biological_process | L-methionine salvage from S-adenosylmethionine |
| A | 0019509 | biological_process | L-methionine salvage from methylthioadenosine |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0008782 | molecular_function | adenosylhomocysteine nucleosidase activity |
| B | 0008930 | molecular_function | methylthioadenosine nucleosidase activity |
| B | 0009116 | biological_process | nucleoside metabolic process |
| B | 0009164 | biological_process | nucleoside catabolic process |
| B | 0019284 | biological_process | L-methionine salvage from S-adenosylmethionine |
| B | 0019509 | biological_process | L-methionine salvage from methylthioadenosine |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0008782 | molecular_function | adenosylhomocysteine nucleosidase activity |
| C | 0008930 | molecular_function | methylthioadenosine nucleosidase activity |
| C | 0009116 | biological_process | nucleoside metabolic process |
| C | 0009164 | biological_process | nucleoside catabolic process |
| C | 0019284 | biological_process | L-methionine salvage from S-adenosylmethionine |
| C | 0019509 | biological_process | L-methionine salvage from methylthioadenosine |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE ADE B 301 |
| Chain | Residue |
| B | ALA77 |
| B | GLY78 |
| B | PHE152 |
| B | MET153 |
| B | VAL172 |
| B | GLU173 |
| B | SER197 |
| B | ASP198 |
| B | TRS302 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE TRS B 302 |
| Chain | Residue |
| B | ALA8 |
| B | GLU12 |
| B | SER76 |
| B | GLU173 |
| B | MET174 |
| B | GLU175 |
| B | ARG194 |
| B | ADE301 |
| C | HIS236 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE ADE A 301 |
| Chain | Residue |
| A | ALA77 |
| A | GLY78 |
| A | PHE152 |
| A | MET153 |
| A | VAL172 |
| A | GLU173 |
| A | SER197 |
| A | ASP198 |
| A | TRS302 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE TRS A 302 |
| Chain | Residue |
| A | ALA8 |
| A | GLU12 |
| A | SER76 |
| A | GLU173 |
| A | MET174 |
| A | GLU175 |
| A | ARG194 |
| A | PHE208 |
| A | ADE301 |
| B | HIS236 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE TRS C 301 |
| Chain | Residue |
| C | ALA8 |
| C | GLU12 |
| C | SER76 |
| C | GLU173 |
| C | MET174 |
| C | GLU175 |
| C | ARG194 |
| C | PHE208 |
| C | ADE302 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE ADE C 302 |
| Chain | Residue |
| C | ALA77 |
| C | GLY78 |
| C | PHE152 |
| C | MET153 |
| C | VAL172 |
| C | GLU173 |
| C | SER197 |
| C | ASP198 |
| C | PHE208 |
| C | TRS301 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_01684","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_01684","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01684","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
