4QDD
Crystal structure of 3-ketosteroid-9-alpha-hydroxylase 5 (KshA5) from R. rhodochrous in complex with 1,4-30Q-CoA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006707 | biological_process | cholesterol catabolic process |
| A | 0008202 | biological_process | steroid metabolic process |
| A | 0008203 | biological_process | cholesterol metabolic process |
| A | 0016042 | biological_process | lipid catabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| A | 0036200 | molecular_function | 3-ketosteroid 9-alpha-monooxygenase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE FES A 401 |
| Chain | Residue |
| A | CYS73 |
| A | HIS75 |
| A | MET76 |
| A | GLY78 |
| A | CYS92 |
| A | PHE94 |
| A | HIS95 |
| A | TRP97 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FE2 A 402 |
| Chain | Residue |
| A | HIS192 |
| A | ASP311 |
| A | HOH501 |
| A | HIS187 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 30Q A 403 |
| Chain | Residue |
| A | ASN181 |
| A | VAL182 |
| A | HIS192 |
| A | GLN210 |
| A | SER235 |
| A | ASP247 |
| A | GLN299 |
| A | PHE300 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00628, ECO:0000269|PubMed:25049233 |
| Chain | Residue | Details |
| A | CYS73 | |
| A | HIS75 | |
| A | CYS92 | |
| A | HIS95 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:25049233 |
| Chain | Residue | Details |
| A | ASN181 | |
| A | HIS187 | |
| A | HIS192 | |
| A | ASP311 |
