4QB9
Crystal structure of Mycobacterium smegmatis Eis in complex with paromomycin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008080 | molecular_function | N-acetyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| A | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| A | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
| B | 0008080 | molecular_function | N-acetyltransferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| B | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| B | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
| C | 0008080 | molecular_function | N-acetyltransferase activity |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016746 | molecular_function | acyltransferase activity |
| C | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| C | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| C | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
| D | 0008080 | molecular_function | N-acetyltransferase activity |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016746 | molecular_function | acyltransferase activity |
| D | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| D | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| D | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
| E | 0008080 | molecular_function | N-acetyltransferase activity |
| E | 0016740 | molecular_function | transferase activity |
| E | 0016746 | molecular_function | acyltransferase activity |
| E | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| E | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| E | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
| F | 0008080 | molecular_function | N-acetyltransferase activity |
| F | 0016740 | molecular_function | transferase activity |
| F | 0016746 | molecular_function | acyltransferase activity |
| F | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| F | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| F | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE PAR A 500 |
| Chain | Residue |
| A | PHE26 |
| A | TYR400 |
| A | GLY401 |
| A | PHE402 |
| A | SO4501 |
| A | SER83 |
| A | PHE84 |
| A | THR119 |
| A | ALA120 |
| A | SER121 |
| A | GLU137 |
| A | ASP290 |
| A | ASP291 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 501 |
| Chain | Residue |
| A | GLU137 |
| A | GLY266 |
| A | ASP291 |
| A | GLU397 |
| A | LEU398 |
| A | PAR500 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PAR B 500 |
| Chain | Residue |
| B | PHE26 |
| B | ILE82 |
| B | SER83 |
| B | PHE84 |
| B | VAL85 |
| B | THR119 |
| B | SER121 |
| B | GLU137 |
| B | ARG205 |
| B | ASP290 |
| B | ASP291 |
| B | TYR400 |
| B | GLY401 |
| B | PHE402 |
| B | SO4501 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 501 |
| Chain | Residue |
| B | GLU137 |
| B | GLY266 |
| B | GLU397 |
| B | LEU398 |
| B | PAR500 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE PAR C 500 |
| Chain | Residue |
| C | PHE26 |
| C | SER83 |
| C | PHE84 |
| C | THR119 |
| C | ALA120 |
| C | SER121 |
| C | GLU137 |
| C | ASP290 |
| C | ASP291 |
| C | TYR400 |
| C | GLY401 |
| C | PHE402 |
| C | SO4501 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 C 501 |
| Chain | Residue |
| C | GLU137 |
| C | GLU238 |
| C | GLY266 |
| C | GLU397 |
| C | LEU398 |
| C | GLY399 |
| C | PAR500 |
| site_id | AC7 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE PAR D 500 |
| Chain | Residue |
| D | PHE26 |
| D | SER83 |
| D | PHE84 |
| D | THR119 |
| D | ALA120 |
| D | SER121 |
| D | GLU137 |
| D | ASP290 |
| D | ASP291 |
| D | TYR400 |
| D | GLY401 |
| D | PHE402 |
| D | SO4501 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 D 501 |
| Chain | Residue |
| D | GLU137 |
| D | VAL237 |
| D | GLY266 |
| D | GLU397 |
| D | PAR500 |
| site_id | AC9 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PAR E 500 |
| Chain | Residue |
| E | PHE26 |
| E | SER83 |
| E | PHE84 |
| E | VAL85 |
| E | THR119 |
| E | ALA120 |
| E | SER121 |
| E | GLU137 |
| E | ASP290 |
| E | ASP291 |
| E | TYR400 |
| E | GLY401 |
| E | PHE402 |
| E | SO4501 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 E 501 |
| Chain | Residue |
| E | GLU137 |
| E | VAL237 |
| E | GLY266 |
| E | GLU397 |
| E | PAR500 |
| site_id | BC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PAR F 500 |
| Chain | Residue |
| F | THR119 |
| F | ALA120 |
| F | SER121 |
| F | TYR126 |
| F | GLU137 |
| F | GLU238 |
| F | ASP290 |
| F | ASP291 |
| F | GLY401 |
| F | PHE402 |
| F | SO4501 |
| F | PHE26 |
| F | SER83 |
| F | PHE84 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 F 501 |
| Chain | Residue |
| F | GLU137 |
| F | GLU238 |
| F | GLU397 |
| F | LEU398 |
| F | PAR500 |
