4Q9D
X-ray structure of a putative thiamin diphosphate-dependent enzyme isolated from Mycobacterium smegmatis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003984 | molecular_function | acetolactate synthase activity |
| A | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| A | 0009097 | biological_process | isoleucine biosynthetic process |
| A | 0009099 | biological_process | L-valine biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0030976 | molecular_function | thiamine pyrophosphate binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003984 | molecular_function | acetolactate synthase activity |
| B | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| B | 0009097 | biological_process | isoleucine biosynthetic process |
| B | 0009099 | biological_process | L-valine biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0030976 | molecular_function | thiamine pyrophosphate binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 601 |
| Chain | Residue |
| A | ASP434 |
| A | LEU459 |
| A | ASN461 |
| A | GLU463 |
| A | FMT603 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT A 602 |
| Chain | Residue |
| A | HOH1086 |
| A | TYR146 |
| A | SER178 |
| A | VAL179 |
| A | HOH1078 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FMT A 603 |
| Chain | Residue |
| A | GLY433 |
| A | ASP434 |
| A | GLY435 |
| A | SER436 |
| A | GLU463 |
| A | TYR464 |
| A | MG601 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 601 |
| Chain | Residue |
| B | ASP434 |
| B | ASN461 |
| B | GLU463 |
| B | FMT603 |
| B | HOH872 |
| B | HOH1051 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT B 602 |
| Chain | Residue |
| B | TYR146 |
| B | SER178 |
| B | VAL179 |
| B | HOH1065 |
| B | HOH1207 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FMT B 603 |
| Chain | Residue |
| B | GLY433 |
| B | ASP434 |
| B | GLY435 |
| B | SER436 |
| B | GLU463 |
| B | MG601 |
