Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K A 601 |
| Chain | Residue |
| A | ALA474 |
| A | ALA475 |
| A | ASN477 |
| A | ASN480 |
| A | HOH887 |
| B | LEU504 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 602 |
| Chain | Residue |
| A | HIS119 |
| A | SER544 |
| A | HOH1078 |
| A | ILE116 |
| A | SER117 |
| A | SER118 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 603 |
| Chain | Residue |
| A | ARG367 |
| A | SER471 |
| A | HOH754 |
| A | HOH776 |
| A | HOH894 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 604 |
| Chain | Residue |
| A | ARG220 |
| A | ARG239 |
| A | SER243 |
| A | TRP524 |
| A | HOH1016 |
| A | HOH1170 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 605 |
| Chain | Residue |
| A | TYR395 |
| A | SER396 |
| A | LYS397 |
| A | ASP398 |
| A | THR402 |
| A | HOH1157 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 606 |
| Chain | Residue |
| A | HIS119 |
| A | TRP524 |
| A | HOH739 |
| A | HOH1078 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 607 |
| Chain | Residue |
| A | ASP288 |
| A | HOH731 |
| A | HOH1220 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 608 |
| Chain | Residue |
| A | TRP306 |
| A | ASN348 |
| A | HOH1104 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 609 |
| Chain | Residue |
| A | PRO129 |
| A | SER132 |
| A | ILE133 |
| A | ASN134 |
| A | HOH797 |
| A | HOH852 |
| A | HOH1056 |
| B | HOH948 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE K B 601 |
| Chain | Residue |
| B | ASN348 |
| B | ASP351 |
| B | EDO605 |
| B | HOH1262 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 602 |
| Chain | Residue |
| B | PHE273 |
| B | TRP306 |
| B | PRO346 |
| B | ASN348 |
| B | HOH706 |
| B | HOH905 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 603 |
| Chain | Residue |
| B | HIS249 |
| B | ASP251 |
| B | ALA272 |
| B | HOH762 |
| B | HOH980 |
| B | HOH1035 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 604 |
| Chain | Residue |
| B | ARG220 |
| B | ARG239 |
| B | SER243 |
| B | TRP524 |
| B | HOH938 |
| B | HOH1150 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 605 |
| Chain | Residue |
| B | ASN348 |
| B | K601 |
| B | EDO607 |
| B | HOH720 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 606 |
| Chain | Residue |
| B | SER471 |
| B | HOH776 |
| B | HOH785 |
| B | HOH870 |
| B | HOH1085 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 607 |
| Chain | Residue |
| B | ASP324 |
| B | MSE325 |
| B | GLN330 |
| B | ASN348 |
| B | EDO605 |
| B | HOH1283 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 608 |
| Chain | Residue |
| B | ASP288 |
| B | HOH724 |
| B | HOH760 |
| B | HOH863 |
| site_id | BC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 609 |
| Chain | Residue |
| B | LYS335 |
| B | SER336 |
| B | THR337 |
| B | ASP338 |
| B | THR342 |
| B | SER344 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 610 |
| Chain | Residue |
| B | LEU173 |
| B | GLY260 |
| B | HOH929 |
| B | HOH956 |
| B | HOH1192 |
| site_id | CC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO B 611 |
| Chain | Residue |
| B | LEU269 |
| B | PRO270 |
| B | TRP343 |
| B | SER344 |
| B | GLU345 |
| B | HOH759 |
| B | HOH888 |
| B | HOH1129 |
| site_id | CC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 612 |
| Chain | Residue |
| B | SER118 |
| B | HIS119 |
| B | GLY523 |
| B | TRP524 |
| B | GLU542 |
| B | SER543 |
| B | HIS547 |
| site_id | CC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 601 |
| Chain | Residue |
| C | ASP288 |
| C | HOH707 |
| C | HOH714 |
| C | HOH748 |
| site_id | CC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 602 |
| Chain | Residue |
| C | SER396 |
| C | LYS397 |
| C | ASP398 |
| C | THR402 |
| C | HOH1122 |
| site_id | CC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 603 |
| Chain | Residue |
| C | ARG367 |
| C | SER471 |
| C | HOH712 |
| C | HOH783 |
| C | HOH953 |
| site_id | CC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 604 |
| Chain | Residue |
| C | SER118 |
| C | HIS119 |
| C | GLY523 |
| C | TRP524 |
| C | GLU542 |
| C | SER543 |
| site_id | CC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO D 601 |
| Chain | Residue |
| D | LYS335 |
| D | SER336 |
| D | THR337 |
| D | ASP338 |
| D | THR342 |
| D | TRP343 |
| D | SER344 |
| site_id | CC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO D 602 |
| Chain | Residue |
| D | ARG367 |
| D | SER471 |
| D | HOH771 |
| D | HOH856 |
| D | HOH1009 |
| site_id | DC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO D 603 |
| Chain | Residue |
| D | ARG220 |
| D | ARG239 |
| D | SER243 |
| D | ASP245 |
| D | TRP524 |
| D | HOH985 |
| site_id | DC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO D 604 |
| Chain | Residue |
| D | TYR395 |
| D | SER396 |
| D | LYS397 |
| D | ASP398 |
| D | THR402 |
| D | HOH939 |
| D | HOH1062 |
| site_id | DC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO D 605 |
| Chain | Residue |
| D | ASP288 |
| D | HOH745 |
| D | HOH751 |
| D | HOH764 |
| site_id | DC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO D 606 |
| Chain | Residue |
| D | HIS249 |
| D | ASP251 |
| D | ALA272 |
| D | HOH770 |
| D | HOH1162 |
| D | HOH1225 |
| site_id | DC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO D 607 |
| Chain | Residue |
| D | PRO270 |
| D | TRP343 |
| D | SER344 |
| D | GLU345 |
| D | HOH786 |
