4Q5R
Crystal Structure of Glutathione S-transferase Bla g 5
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004364 | molecular_function | glutathione transferase activity |
| A | 0004602 | molecular_function | glutathione peroxidase activity |
| A | 0006749 | biological_process | glutathione metabolic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| B | 0004364 | molecular_function | glutathione transferase activity |
| B | 0004602 | molecular_function | glutathione peroxidase activity |
| B | 0006749 | biological_process | glutathione metabolic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0098869 | biological_process | cellular oxidant detoxification |
| C | 0004364 | molecular_function | glutathione transferase activity |
| C | 0004602 | molecular_function | glutathione peroxidase activity |
| C | 0006749 | biological_process | glutathione metabolic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0098869 | biological_process | cellular oxidant detoxification |
| D | 0004364 | molecular_function | glutathione transferase activity |
| D | 0004602 | molecular_function | glutathione peroxidase activity |
| D | 0006749 | biological_process | glutathione metabolic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0098869 | biological_process | cellular oxidant detoxification |
| E | 0004364 | molecular_function | glutathione transferase activity |
| E | 0004602 | molecular_function | glutathione peroxidase activity |
| E | 0006749 | biological_process | glutathione metabolic process |
| E | 0016740 | molecular_function | transferase activity |
| E | 0098869 | biological_process | cellular oxidant detoxification |
| F | 0004364 | molecular_function | glutathione transferase activity |
| F | 0004602 | molecular_function | glutathione peroxidase activity |
| F | 0006749 | biological_process | glutathione metabolic process |
| F | 0016740 | molecular_function | transferase activity |
| F | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE GSH A 301 |
| Chain | Residue |
| A | TYR9 |
| A | SER65 |
| A | GSH303 |
| A | HOH416 |
| A | HOH417 |
| A | HOH427 |
| A | HOH480 |
| B | ASP98 |
| A | LEU15 |
| A | TRP40 |
| A | LYS44 |
| A | GLY50 |
| A | LYS51 |
| A | THR52 |
| A | PRO53 |
| A | GLN64 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GSH A 302 |
| Chain | Residue |
| A | CYS10 |
| A | GSH303 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GSH A 303 |
| Chain | Residue |
| A | GSH301 |
| A | GSH302 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 304 |
| Chain | Residue |
| A | LYS44 |
| A | PHE49 |
| A | GLY50 |
| B | THR126 |
| B | TYR129 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE GSH C 301 |
| Chain | Residue |
| C | TYR9 |
| C | LEU15 |
| C | TRP40 |
| C | LYS44 |
| C | GLY50 |
| C | LYS51 |
| C | THR52 |
| C | GLN64 |
| C | SER65 |
| C | GSH302 |
| C | HOH406 |
| C | HOH408 |
| C | HOH457 |
| D | ASP98 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GSH C 302 |
| Chain | Residue |
| C | TYR108 |
| C | GSH301 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL C 303 |
| Chain | Residue |
| C | LYS44 |
| C | PHE49 |
| C | GLY50 |
| C | LYS51 |
| D | TYR129 |
| site_id | AC8 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE GSH D 301 |
| Chain | Residue |
| C | ASP98 |
| D | CYS10 |
| D | LEU15 |
| D | TRP40 |
| D | LYS44 |
| D | LYS51 |
| D | THR52 |
| D | PRO53 |
| D | GLN64 |
| D | SER65 |
| D | HOH411 |
| D | HOH413 |
| D | HOH427 |
| D | HOH520 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL D 302 |
| Chain | Residue |
| C | TYR129 |
| D | LYS44 |
| D | PHE49 |
| D | GLY50 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL D 303 |
| Chain | Residue |
| D | CYS10 |
| D | ALA14 |
| D | GLY16 |
| D | ARG20 |
| site_id | BC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE GSH B 301 |
| Chain | Residue |
| A | ASP98 |
| B | TYR9 |
| B | LEU15 |
| B | TRP40 |
| B | LYS44 |
| B | LYS51 |
| B | THR52 |
| B | GLN64 |
| B | SER65 |
| B | GSH302 |
| B | GSH303 |
| B | HOH416 |
| B | HOH418 |
| B | HOH424 |
| B | HOH442 |
| B | HOH479 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GSH B 302 |
| Chain | Residue |
| B | CYS10 |
| B | GSH301 |
| B | GSH303 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GSH B 303 |
| Chain | Residue |
| B | TYR108 |
| B | GSH301 |
| B | GSH302 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 304 |
| Chain | Residue |
| A | GLU125 |
| A | TYR129 |
| B | LYS44 |
| B | PHE49 |
| B | GLY50 |
| site_id | BC6 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE GSH F 500 |
| Chain | Residue |
| F | LYS51 |
| F | THR52 |
| F | PRO53 |
| F | GLN64 |
| F | SER65 |
| F | GSH502 |
| F | HOH602 |
| F | HOH605 |
| F | HOH624 |
| E | ASP98 |
| F | TYR9 |
| F | TRP40 |
| F | LYS44 |
| site_id | BC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GSH F 501 |
| Chain | Residue |
| F | CYS10 |
| site_id | BC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GSH F 502 |
| Chain | Residue |
| F | TYR9 |
| F | GSH500 |
| site_id | BC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GSH E 500 |
| Chain | Residue |
| E | TYR9 |
| E | LEU15 |
| E | THR52 |
| E | GLN64 |
| E | SER65 |
| E | HOH626 |
| F | ASP98 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 385 |
| Details | Domain: {"description":"GST N-terminal"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 488 |
| Details | Domain: {"description":"GST C-terminal"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 30 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"O60760","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P46088","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
