4Q5O
Crystal structure of EctD from S. alaskensis with 2-oxoglutarate and 5-hydroxyectoine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016706 | molecular_function | 2-oxoglutarate-dependent dioxygenase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051213 | molecular_function | dioxygenase activity |
| B | 0005506 | molecular_function | iron ion binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016706 | molecular_function | 2-oxoglutarate-dependent dioxygenase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051213 | molecular_function | dioxygenase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE A 401 |
| Chain | Residue |
| A | HIS144 |
| A | ASP146 |
| A | HIS245 |
| A | AKG402 |
| A | 6CS403 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE AKG A 402 |
| Chain | Residue |
| A | PHE260 |
| A | FE401 |
| A | HOH508 |
| A | ASN131 |
| A | LYS133 |
| A | PHE141 |
| A | HIS245 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 6CS A 403 |
| Chain | Residue |
| A | GLN127 |
| A | ARG129 |
| A | PHE141 |
| A | HIS144 |
| A | ASP146 |
| A | ARG280 |
| A | FE401 |
| A | HOH508 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE B 401 |
| Chain | Residue |
| B | HIS144 |
| B | ASP146 |
| B | HIS245 |
| B | AKG402 |
| B | 6CS403 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE AKG B 402 |
| Chain | Residue |
| B | ARG129 |
| B | ASN131 |
| B | PHE141 |
| B | HIS144 |
| B | ASP146 |
| B | HIS245 |
| B | SER247 |
| B | ARG256 |
| B | PHE260 |
| B | FE401 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 6CS B 403 |
| Chain | Residue |
| B | GLN127 |
| B | ARG129 |
| B | HIS144 |
| B | ASP146 |
| B | TRP150 |
| B | ARG280 |
| B | FE401 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25172507","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"4Q5O","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25172507","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4Q5O","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25172507","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4MHU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4Q5O","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Site: {"description":"Important for ectoine stabilization","evidences":[{"source":"PubMed","id":"25172507","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
