Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE ROC A 1101 |
| Chain | Residue |
| A | ARG8 |
| A | THR80 |
| A | PRO81 |
| A | VAL82 |
| A | ILE84 |
| A | ARG1008 |
| A | ASP1025 |
| A | GLY1027 |
| A | ALA1028 |
| A | ASP1029 |
| A | ASN1030 |
| A | ASP25 |
| A | GLY1048 |
| A | GLY1049 |
| A | ILE1050 |
| A | PRO1081 |
| A | VAL1082 |
| A | ILE1084 |
| A | HOH1201 |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| A | ASN30 |
| A | GLY48 |
| A | GLY49 |
| A | ILE50 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADNTVL |
| Chain | Residue | Details |
| A | ALA22-LEU33 | |
| A | ALA1022-LEU1033 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP1025 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| A | PHE1099 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 3 |
| Details | M-CSA 175 |
| Chain | Residue | Details |
| A | ASP1025 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | THR1026 | electrostatic stabiliser, transition state stabiliser |
| A | GLY1027 | electrostatic stabiliser, hydrogen bond donor |
