4Q5F

Crystal Structure of the Glutathione S-transferase from Ascaris lumbricoides

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004364	molecular_function	glutathione transferase activity
A	0004602	molecular_function	glutathione peroxidase activity
A	0005737	cellular_component	cytoplasm
A	0005903	cellular_component	brush border
A	0006749	biological_process	glutathione metabolic process
A	0016740	molecular_function	transferase activity
A	0098869	biological_process	cellular oxidant detoxification
D	0004364	molecular_function	glutathione transferase activity
D	0004602	molecular_function	glutathione peroxidase activity
D	0005737	cellular_component	cytoplasm
D	0005903	cellular_component	brush border
D	0006749	biological_process	glutathione metabolic process
D	0016740	molecular_function	transferase activity
D	0098869	biological_process	cellular oxidant detoxification

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	BINDING SITE FOR RESIDUE GSH A 301

Chain	Residue
A	TYR8
A	SER64
A	HOH403
A	HOH468
D	GLU37
D	ASP97
A	LEU14
A	TRP39
A	LYS43
A	GLY49
A	GLN50
A	LEU51
A	PRO52
A	GLN63

---

site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE GSH A 302

Chain	Residue
A	CYS105

---

site_id	AC3
Number of Residues	12
Details	BINDING SITE FOR RESIDUE GSH D 301

Chain	Residue
A	GLU37
A	ASP97
D	TYR8
D	LEU14
D	TRP39
D	LYS43
D	GLN50
D	LEU51
D	PRO52
D	GLN63
D	SER64
D	HOH404

---

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GSH D 302

Chain	Residue
D	PRO104
D	CYS105

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	154
Details	Domain: {"description":"GST N-terminal"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	250
Details	Domain: {"description":"GST C-terminal"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"O60760","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P46088","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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