4Q43
Polymerase-damaged DNA complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0000731 | biological_process | DNA synthesis involved in DNA repair |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003684 | molecular_function | damaged DNA binding |
| A | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006260 | biological_process | DNA replication |
| A | 0006261 | biological_process | DNA-templated DNA replication |
| A | 0006281 | biological_process | DNA repair |
| A | 0006974 | biological_process | DNA damage response |
| A | 0008296 | molecular_function | 3'-5'-DNA exonuclease activity |
| A | 0009432 | biological_process | SOS response |
| A | 0042276 | biological_process | error-prone translesion synthesis |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0070987 | biological_process | error-free translesion synthesis |
| F | 0000287 | molecular_function | magnesium ion binding |
| F | 0000731 | biological_process | DNA synthesis involved in DNA repair |
| F | 0003677 | molecular_function | DNA binding |
| F | 0003684 | molecular_function | damaged DNA binding |
| F | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| F | 0005515 | molecular_function | protein binding |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0006260 | biological_process | DNA replication |
| F | 0006261 | biological_process | DNA-templated DNA replication |
| F | 0006281 | biological_process | DNA repair |
| F | 0006974 | biological_process | DNA damage response |
| F | 0008296 | molecular_function | 3'-5'-DNA exonuclease activity |
| F | 0009432 | biological_process | SOS response |
| F | 0042276 | biological_process | error-prone translesion synthesis |
| F | 0046872 | molecular_function | metal ion binding |
| F | 0070987 | biological_process | error-free translesion synthesis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE 0KX A 401 |
| Chain | Residue |
| A | ASP8 |
| A | ASP103 |
| A | LYS157 |
| A | MG402 |
| A | MG403 |
| A | HOH504 |
| A | HOH510 |
| B | RDG840 |
| C | DC873 |
| A | MET9 |
| A | ASP10 |
| A | CYS11 |
| A | PHE12 |
| A | PHE13 |
| A | SER42 |
| A | THR43 |
| A | ARG49 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 402 |
| Chain | Residue |
| A | ASP8 |
| A | MET9 |
| A | ASP103 |
| A | 0KX401 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 403 |
| Chain | Residue |
| A | ASP8 |
| A | GLU104 |
| A | 0KX401 |
| C | DC873 |
| site_id | AC4 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE 0KX F 401 |
| Chain | Residue |
| F | ASP8 |
| F | MET9 |
| F | ASP10 |
| F | CYS11 |
| F | PHE12 |
| F | PHE13 |
| F | SER42 |
| F | THR43 |
| F | ARG49 |
| F | SER55 |
| F | ASP103 |
| F | GLU104 |
| F | LYS157 |
| F | MG402 |
| F | MG403 |
| F | HOH507 |
| F | HOH516 |
| F | HOH530 |
| F | HOH546 |
| G | RDG840 |
| H | DC873 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG F 402 |
| Chain | Residue |
| F | ASP8 |
| F | MET9 |
| F | ASP103 |
| F | LYS157 |
| F | 0KX401 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG F 403 |
| Chain | Residue |
| F | SER101 |
| F | ASP103 |
| F | GLU104 |
| F | 0KX401 |
| H | DC873 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250 |
| Chain | Residue | Details |
| A | GLU104 | |
| F | GLU104 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP8 | |
| A | ASP103 | |
| F | ASP8 | |
| F | ASP103 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Substrate discrimination => ECO:0000250 |
| Chain | Residue | Details |
| A | PHE13 | |
| F | PHE13 |
