Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004029 | molecular_function | aldehyde dehydrogenase (NAD+) activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004029 | molecular_function | aldehyde dehydrogenase (NAD+) activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE NAD A 601 |
| Chain | Residue |
| A | ILE166 |
| A | GLY230 |
| A | ALA231 |
| A | PHE244 |
| A | THR245 |
| A | GLY246 |
| A | SER247 |
| A | VAL250 |
| A | GLU269 |
| A | LEU270 |
| A | GLY271 |
| A | VAL167 |
| A | CSO303 |
| A | GLN350 |
| A | LYS353 |
| A | GLU400 |
| A | PHE402 |
| A | CA611 |
| A | HOH724 |
| A | HOH803 |
| A | PRO168 |
| A | TRP169 |
| A | ASN170 |
| A | LYS193 |
| A | ALA195 |
| A | GLU196 |
| A | GLY226 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 602 |
| Chain | Residue |
| A | VAL332 |
| A | GLY376 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG A 603 |
| Chain | Residue |
| A | GLU325 |
| A | LYS329 |
| B | TYR357 |
| B | ILE360 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 604 |
| Chain | Residue |
| A | GLY272 |
| A | LYS273 |
| A | SER274 |
| A | PRO275 |
| A | TYR426 |
| A | GLY427 |
| A | LEU428 |
| A | ALA429 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PEG A 605 |
| Chain | Residue |
| A | ASN436 |
| A | ASP438 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO A 606 |
| Chain | Residue |
| A | THR144 |
| A | LEU145 |
| A | LYS146 |
| A | HOH729 |
| B | VAL140 |
| B | GLY142 |
| B | THR155 |
| B | LEU156 |
| B | LYS157 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG A 607 |
| Chain | Residue |
| B | PHE279 |
| B | ASP281 |
| B | GLN312 |
| B | VAL414 |
| B | VAL439 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 609 |
| Chain | Residue |
| A | THR41 |
| A | ARG42 |
| A | ASP110 |
| A | GLN197 |
| A | HOH829 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG A 610 |
| Chain | Residue |
| A | TYR171 |
| A | THR174 |
| A | PHE458 |
| A | PHE460 |
| A | HOH821 |
| site_id | BC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CA A 611 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 612 |
| Chain | Residue |
| A | THR248 |
| A | GLU249 |
| A | ARG252 |
| A | ARG425 |
| A | MET471 |
| site_id | BC3 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE NAD B 601 |
| Chain | Residue |
| B | ILE166 |
| B | VAL167 |
| B | PRO168 |
| B | TRP169 |
| B | ASN170 |
| B | LYS193 |
| B | ALA195 |
| B | GLU196 |
| B | GLY226 |
| B | GLY230 |
| B | ALA231 |
| B | PHE244 |
| B | THR245 |
| B | GLY246 |
| B | SER247 |
| B | VAL250 |
| B | LEU253 |
| B | GLU269 |
| B | LEU270 |
| B | GLY271 |
| B | CYS303 |
| B | GLN350 |
| B | LYS353 |
| B | GLU400 |
| B | PHE402 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 602 |
| Chain | Residue |
| B | ASN441 |
| B | THR442 |
| B | PRO495 |
| B | LEU496 |
| B | TYR497 |
| B | ASP438 |
| site_id | BC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO B 603 |
| Chain | Residue |
| B | ASP438 |
| B | TYR497 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA B 604 |
| Chain | Residue |
| B | THR41 |
| B | ARG42 |
| B | ASP110 |
| B | GLN197 |
| B | HOH812 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 605 |
| Chain | Residue |
| A | ASN498 |
| A | THR499 |
| A | PRO500 |
| B | ARG79 |
| site_id | BC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO B 606 |
| Chain | Residue |
| B | GLU260 |
| B | SER261 |
Functional Information from PROSITE/UniProt
| site_id | PS00070 |
| Number of Residues | 12 |
| Details | ALDEHYDE_DEHYDR_CYS Aldehyde dehydrogenases cysteine active site. YtNKGEICVAGT |
| Chain | Residue | Details |
| A | TYR296-THR307 | |
| B | TYR296-THR307 | |
| site_id | PS00687 |
| Number of Residues | 8 |
| Details | ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. LELGGKSP |
| Chain | Residue | Details |
| A | LEU268-PRO275 | |
| B | LEU268-PRO275 | |
