4PX1

CRYSTAL STRUCTURE OF Maleylacetoacetate isomerase from Methylobacteriu extorquens AM1 WITH BOUND MALONATE (TARGET EFI-507068)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004364	molecular_function	glutathione transferase activity
A	0005737	cellular_component	cytoplasm
A	0006559	biological_process	L-phenylalanine catabolic process
A	0006749	biological_process	glutathione metabolic process
A	0009072	biological_process	aromatic amino acid metabolic process
A	0016034	molecular_function	maleylacetoacetate isomerase activity
A	0016740	molecular_function	transferase activity
A	0016853	molecular_function	isomerase activity
B	0003824	molecular_function	catalytic activity
B	0004364	molecular_function	glutathione transferase activity
B	0005737	cellular_component	cytoplasm
B	0006559	biological_process	L-phenylalanine catabolic process
B	0006749	biological_process	glutathione metabolic process
B	0009072	biological_process	aromatic amino acid metabolic process
B	0016034	molecular_function	maleylacetoacetate isomerase activity
B	0016740	molecular_function	transferase activity
B	0016853	molecular_function	isomerase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE MLA A 301

Chain	Residue
A	ARG8
A	HOH468
A	SER9
A	ALA10
A	HIS105
A	PRO110
A	ARG113
A	HOH414
A	HOH442
A	HOH466

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 302

Chain	Residue
A	GLN49
A	THR64
A	GLN65
A	HOH500
B	ARG145

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site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE MLA B 301

Chain	Residue
B	ARG8
B	SER9
B	ALA10
B	HIS105
B	PRO110
B	ARG113
B	HOH406
B	HOH454
B	HOH466
B	HOH484

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