4PR3
Crystal structure of Brucella melitensis 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0008782 | molecular_function | adenosylhomocysteine nucleosidase activity |
| A | 0008930 | molecular_function | methylthioadenosine nucleosidase activity |
| A | 0009116 | biological_process | nucleoside metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0008782 | molecular_function | adenosylhomocysteine nucleosidase activity |
| B | 0008930 | molecular_function | methylthioadenosine nucleosidase activity |
| B | 0009116 | biological_process | nucleoside metabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE ADE A 501 |
| Chain | Residue |
| A | SER65 |
| A | ASP168 |
| A | ALA66 |
| A | GLY67 |
| A | ILE128 |
| A | VAL129 |
| A | VAL142 |
| A | ASP143 |
| A | MSE144 |
| A | SER167 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 A 502 |
| Chain | Residue |
| A | SER83 |
| A | SER123 |
| A | ILE137 |
| A | GLU138 |
| A | ALA139 |
| A | HOH635 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE ADE B 501 |
| Chain | Residue |
| B | SER65 |
| B | ALA66 |
| B | GLY67 |
| B | ASN127 |
| B | ILE128 |
| B | VAL129 |
| B | TYR134 |
| B | VAL142 |
| B | ASP143 |
| B | MSE144 |
| B | SER167 |
| B | ASP168 |
| B | HOH630 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 B 502 |
| Chain | Residue |
| B | SER83 |
| B | ARG85 |
| B | GLU106 |
| B | SER123 |
| B | ILE137 |
| B | GLU138 |
| B | ALA139 |
| B | HOH627 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 503 |
| Chain | Residue |
| B | GLY97 |
| B | VAL98 |
| B | THR99 |
| B | LEU104 |
| B | PRO105 |
| B | VAL108 |
| B | TYR147 |
