4PP0
Structure of the PBP NocT-M117N in complex with pyronopaline
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| A | 0016020 | cellular_component | membrane |
| A | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| A | 0034220 | biological_process | monoatomic ion transmembrane transport |
| A | 0042597 | cellular_component | periplasmic space |
| A | 0071705 | biological_process | nitrogen compound transport |
| B | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| B | 0016020 | cellular_component | membrane |
| B | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| B | 0034220 | biological_process | monoatomic ion transmembrane transport |
| B | 0042597 | cellular_component | periplasmic space |
| B | 0071705 | biological_process | nitrogen compound transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE OP1 A 301 |
| Chain | Residue |
| A | GLU36 |
| A | THR168 |
| A | SER169 |
| A | HIS170 |
| A | SER207 |
| A | SER209 |
| A | PHE235 |
| A | HOH405 |
| A | TYR39 |
| A | TRP77 |
| A | ALA94 |
| A | ALA95 |
| A | GLY97 |
| A | ARG102 |
| A | ASN117 |
| A | GLN165 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 302 |
| Chain | Residue |
| A | PRO41 |
| A | LYS217 |
| A | TRP274 |
| A | HOH408 |
| A | HOH642 |
| A | HOH684 |
| B | HOH555 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 303 |
| Chain | Residue |
| A | THR32 |
| A | ARG88 |
| A | TYR89 |
| A | HOH593 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 304 |
| Chain | Residue |
| A | PRO144 |
| A | HOH459 |
| A | HOH704 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 305 |
| Chain | Residue |
| A | GLN272 |
| A | TYR277 |
| A | ASP278 |
| A | HOH685 |
| A | HOH708 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG A 306 |
| Chain | Residue |
| A | GLN75 |
| A | ALA76 |
| A | GLY79 |
| A | LYS155 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG A 307 |
| Chain | Residue |
| A | LYS104 |
| A | LYS175 |
| A | EDO310 |
| A | HOH481 |
| A | HOH681 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 308 |
| Chain | Residue |
| A | GLU103 |
| A | PRO179 |
| A | SER180 |
| A | GLN182 |
| A | HOH443 |
| A | HOH625 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 309 |
| Chain | Residue |
| A | ARG65 |
| A | ASN67 |
| B | GLN176 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 310 |
| Chain | Residue |
| A | LYS104 |
| A | LYS175 |
| A | ILE183 |
| A | THR185 |
| A | PEG307 |
| A | HOH421 |
| A | HOH501 |
| site_id | BC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE OP1 B 301 |
| Chain | Residue |
| B | GLU36 |
| B | TYR39 |
| B | TRP77 |
| B | ALA94 |
| B | ALA95 |
| B | GLY97 |
| B | ARG102 |
| B | ASN117 |
| B | GLN165 |
| B | THR168 |
| B | SER169 |
| B | HIS170 |
| B | SER207 |
| B | HOH401 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG B 302 |
| Chain | Residue |
| B | LEU139 |
| B | ASP140 |
| B | MET177 |
| B | GLY233 |
| B | LEU234 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 303 |
| Chain | Residue |
| B | ALA133 |
| B | ILE134 |
| B | GLU135 |
| B | ASN136 |
| B | HOH563 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 304 |
| Chain | Residue |
| B | LYS212 |
| B | ARG229 |
| B | HOH568 |
| site_id | BC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO B 305 |
| Chain | Residue |
| B | ALA40 |
| B | PRO41 |
| B | PRO213 |
| B | LEU214 |
| B | LYS217 |
| B | HOH413 |
| B | HOH427 |
| B | HOH461 |
Functional Information from PROSITE/UniProt
| site_id | PS01039 |
| Number of Residues | 14 |
| Details | SBP_BACTERIAL_3 Bacterial extracellular solute-binding proteins, family 3 signature. GFDIDLGNdLCKRM |
| Chain | Residue | Details |
| A | GLY53-MET66 |
