4PNF
Glutathione S-Transferase from Drosophila melanogaster - isozyme E6
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004364 | molecular_function | glutathione transferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006749 | biological_process | glutathione metabolic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004364 | molecular_function | glutathione transferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006749 | biological_process | glutathione metabolic process |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004364 | molecular_function | glutathione transferase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006749 | biological_process | glutathione metabolic process |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004364 | molecular_function | glutathione transferase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006749 | biological_process | glutathione metabolic process |
| E | 0003824 | molecular_function | catalytic activity |
| E | 0004364 | molecular_function | glutathione transferase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0006749 | biological_process | glutathione metabolic process |
| F | 0003824 | molecular_function | catalytic activity |
| F | 0004364 | molecular_function | glutathione transferase activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0006749 | biological_process | glutathione metabolic process |
| G | 0003824 | molecular_function | catalytic activity |
| G | 0004364 | molecular_function | glutathione transferase activity |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0006749 | biological_process | glutathione metabolic process |
| H | 0003824 | molecular_function | catalytic activity |
| H | 0004364 | molecular_function | glutathione transferase activity |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0006749 | biological_process | glutathione metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue GSH A 2001 |
| Chain | Residue |
| A | SER12 |
| A | HIS69 |
| A | PHE108 |
| A | ARG113 |
| A | HOH2116 |
| A | HOH2119 |
| A | HOH2123 |
| A | HOH2133 |
| A | HOH2140 |
| A | HOH2149 |
| A | PRO14 |
| A | GLN41 |
| A | HIS53 |
| A | THR54 |
| A | VAL55 |
| A | PRO56 |
| A | ASP67 |
| A | SER68 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | binding site for residue GSH B 2001 |
| Chain | Residue |
| B | SER12 |
| B | PRO14 |
| B | GLN41 |
| B | HIS53 |
| B | THR54 |
| B | VAL55 |
| B | PRO56 |
| B | ASP67 |
| B | SER68 |
| B | HIS69 |
| B | PHE108 |
| B | ARG113 |
| B | HOH2112 |
| B | HOH2116 |
| B | HOH2122 |
| B | HOH2129 |
| B | HOH2130 |
| B | HOH2133 |
| site_id | AC3 |
| Number of Residues | 19 |
| Details | binding site for residue GSH C 2001 |
| Chain | Residue |
| C | SER12 |
| C | PRO14 |
| C | GLN41 |
| C | HIS53 |
| C | THR54 |
| C | VAL55 |
| C | PRO56 |
| C | ASP67 |
| C | SER68 |
| C | HIS69 |
| C | PHE108 |
| C | ARG113 |
| C | HOH2129 |
| C | HOH2132 |
| C | HOH2133 |
| C | HOH2140 |
| C | HOH2146 |
| C | HOH2177 |
| C | HOH2199 |
| site_id | AC4 |
| Number of Residues | 17 |
| Details | binding site for residue GSH D 2001 |
| Chain | Residue |
| D | SER12 |
| D | PRO14 |
| D | GLN41 |
| D | HIS53 |
| D | THR54 |
| D | VAL55 |
| D | ASP67 |
| D | SER68 |
| D | HIS69 |
| D | PHE108 |
| D | ARG113 |
| D | HOH2141 |
| D | HOH2147 |
| D | HOH2149 |
| D | HOH2160 |
| D | HOH2212 |
| D | HOH2229 |
| site_id | AC5 |
| Number of Residues | 18 |
| Details | binding site for residue GSH E 2001 |
| Chain | Residue |
| E | SER12 |
| E | PRO14 |
| E | GLN41 |
| E | HIS53 |
| E | THR54 |
| E | VAL55 |
| E | PRO56 |
| E | ASP67 |
| E | SER68 |
| E | HIS69 |
| E | PHE108 |
| E | ARG113 |
| E | HOH2119 |
| E | HOH2124 |
| E | HOH2128 |
| E | HOH2141 |
| E | HOH2142 |
| E | HOH2143 |
| site_id | AC6 |
| Number of Residues | 17 |
| Details | binding site for residue GSH F 2001 |
| Chain | Residue |
| F | PHE108 |
| F | ARG113 |
| F | HOH2128 |
| F | HOH2131 |
| F | HOH2135 |
| F | HOH2137 |
| F | HOH2149 |
| F | HOH2150 |
| F | SER12 |
| F | PRO14 |
| F | GLN41 |
| F | HIS53 |
| F | THR54 |
| F | VAL55 |
| F | ASP67 |
| F | SER68 |
| F | HIS69 |
| site_id | AC7 |
| Number of Residues | 18 |
| Details | binding site for residue GSH G 2001 |
| Chain | Residue |
| G | SER12 |
| G | PRO14 |
| G | GLN41 |
| G | HIS53 |
| G | THR54 |
| G | VAL55 |
| G | PRO56 |
| G | ASP67 |
| G | SER68 |
| G | HIS69 |
| G | PHE108 |
| G | ARG113 |
| G | HOH2117 |
| G | HOH2122 |
| G | HOH2123 |
| G | HOH2127 |
| G | HOH2129 |
| G | HOH2140 |
| site_id | AC8 |
| Number of Residues | 18 |
| Details | binding site for residue GSH H 2001 |
| Chain | Residue |
| H | SER12 |
| H | PRO14 |
| H | GLN41 |
| H | HIS53 |
| H | THR54 |
| H | VAL55 |
| H | ASP67 |
| H | SER68 |
| H | HIS69 |
| H | PHE108 |
| H | ARG113 |
| H | HOH2134 |
| H | HOH2136 |
| H | HOH2139 |
| H | HOH2140 |
| H | HOH2144 |
| H | HOH2147 |
| H | HOH2170 |
