4PLN

Crystal Structure of Chicken Netrin-1 (LN-LE3) complexed with mouse Neogenin (FN4-5)

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0005887	cellular_component	integral component of plasma membrane
C	0007399	biological_process	nervous system development
C	0007411	biological_process	axon guidance
C	0030513	biological_process	positive regulation of BMP signaling pathway
C	0038023	molecular_function	signaling receptor activity
C	0055072	biological_process	iron ion homeostasis
D	0005887	cellular_component	integral component of plasma membrane
D	0007399	biological_process	nervous system development
D	0007411	biological_process	axon guidance
D	0030513	biological_process	positive regulation of BMP signaling pathway
D	0038023	molecular_function	signaling receptor activity
D	0055072	biological_process	iron ion homeostasis

Functional Information from PROSITE/UniProt

site_id	PS00022
Number of Residues	12
Details	EGF_1 EGF-like domain signature 1. CdCkhNtaGPeC

Chain	Residue	Details
A	CYS306-CYS317
A	CYS425-CYS436

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site_id	PS01248
Number of Residues	35
Details	EGF_LAM_1 Laminin-type EGF-like (LE) domain signature. Cd.CkhntaGpeCdrCkpfhYdrpwqratareane.C

Chain	Residue	Details
A	CYS306-CYS340
A	CYS370-CYS406
A	CYS425-CYS453

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
C	LEU940
D	LEU940
A	ASN133
A	ASN419
B	ASN97
B	ASN118
B	ASN133
B	ASN419

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