Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| A | 0007165 | biological_process | signal transduction |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| B | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| B | 0007165 | biological_process | signal transduction |
| B | 0008081 | molecular_function | phosphoric diester hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue ZN A 801 |
| Chain | Residue |
| A | HIS519 |
| A | HIS553 |
| A | ASP554 |
| A | ASP664 |
| A | ZN802 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue ZN A 802 |
| Chain | Residue |
| A | HOH960 |
| A | HOH961 |
| A | ASP554 |
| A | ZN801 |
| A | HOH957 |
| A | HOH958 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 803 |
| Chain | Residue |
| A | LYS497 |
| A | GLY597 |
| A | HIS598 |
| A | ASN599 |
| A | SER602 |
| A | HOH923 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 804 |
| Chain | Residue |
| A | LEU537 |
| A | LEU646 |
| A | ASN647 |
| A | ARG652 |
| B | LEU537 |
| B | LEU646 |
| B | ASN647 |
| B | ARG652 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | binding site for residue 2W1 A 805 |
| Chain | Residue |
| A | SER667 |
| A | VAL668 |
| A | ILE682 |
| A | TYR683 |
| A | PHE686 |
| A | PRO702 |
| A | MET703 |
| A | LYS708 |
| A | GLU711 |
| A | VAL712 |
| A | GLY715 |
| A | GLN716 |
| A | PHE719 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue ZN B 801 |
| Chain | Residue |
| B | HIS519 |
| B | HIS553 |
| B | ASP554 |
| B | ASP664 |
| B | ZN802 |
| B | HOH912 |
| B | HOH963 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue ZN B 802 |
| Chain | Residue |
| B | ASP554 |
| B | ZN801 |
| B | HOH912 |
| B | HOH951 |
| B | HOH961 |
| B | HOH965 |
| B | HOH966 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 803 |
| Chain | Residue |
| B | LYS497 |
| B | GLY597 |
| B | HIS598 |
| B | ASN599 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 804 |
| Chain | Residue |
| B | ARG510 |
| B | ARG511 |
| site_id | AD1 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 B 805 |
| Chain | Residue |
| B | SER605 |
| B | SER605 |
| B | SER605 |
| B | SER606 |
| B | SER606 |
| B | SER606 |
| B | HOH907 |
| B | HOH907 |
| B | HOH907 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 806 |
| Chain | Residue |
| B | ASN599 |
| B | PHE601 |
| B | SER602 |
| B | LEU604 |
| B | TYR609 |
| site_id | AD3 |
| Number of Residues | 12 |
| Details | binding site for residue 2W1 B 807 |
| Chain | Residue |
| B | SER667 |
| B | VAL668 |
| B | ILE682 |
| B | TYR683 |
| B | PHE686 |
| B | PRO702 |
| B | MET703 |
| B | VAL712 |
| B | GLY715 |
| B | GLN716 |
| B | PHE719 |
| B | HOH962 |
Functional Information from PROSITE/UniProt
| site_id | PS00126 |
| Number of Residues | 12 |
| Details | PDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDLdHrGfsNsY |
| Chain | Residue | Details |
| A | HIS553-TYR564 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASN562 | |
| A | SER606 | |
| A | GLN640 | |
| A | MET659 | |
| B | ASN562 | |
| B | SER606 | |
| B | GLN640 | |
| B | MET659 | |
