4PG2

The crystal structure of H-2Db with a S-glutathionylated peptide

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0001913	biological_process	T cell mediated cytotoxicity
C	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
C	0002237	biological_process	response to molecule of bacterial origin
C	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
C	0002481	biological_process	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
C	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
C	0002726	biological_process	positive regulation of T cell cytokine production
C	0005198	molecular_function	structural molecule activity
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005615	cellular_component	extracellular space
C	0005794	cellular_component	Golgi apparatus
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0006826	biological_process	iron ion transport
C	0006879	biological_process	intracellular iron ion homeostasis
C	0006955	biological_process	immune response
C	0006968	biological_process	cellular defense response
C	0007608	biological_process	sensory perception of smell
C	0007611	biological_process	learning or memory
C	0009897	cellular_component	external side of plasma membrane
C	0010977	biological_process	negative regulation of neuron projection development
C	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
C	0030670	cellular_component	phagocytic vesicle membrane
C	0033077	biological_process	T cell differentiation in thymus
C	0034756	biological_process	regulation of iron ion transport
C	0042026	biological_process	protein refolding
C	0042612	cellular_component	MHC class I protein complex
C	0042802	molecular_function	identical protein binding
C	0042803	molecular_function	protein homodimerization activity
C	0042824	cellular_component	MHC class I peptide loading complex
C	0045646	biological_process	regulation of erythrocyte differentiation
C	0048260	biological_process	positive regulation of receptor-mediated endocytosis
C	0050680	biological_process	negative regulation of epithelial cell proliferation
C	0050768	biological_process	negative regulation of neurogenesis
C	0051289	biological_process	protein homotetramerization
C	0060586	biological_process	multicellular organismal-level iron ion homeostasis
C	0071281	biological_process	cellular response to iron ion
C	0071283	biological_process	cellular response to iron(III) ion
C	0071316	biological_process	cellular response to nicotine
C	1990000	biological_process	amyloid fibril formation
C	1990712	cellular_component	HFE-transferrin receptor complex
C	2000774	biological_process	positive regulation of cellular senescence
C	2000978	biological_process	negative regulation of forebrain neuron differentiation

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue SO4 A 301

Chain	Residue
A	GLN87
A	GLN87
A	HIS93
A	GLU119
C	MET0

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site_id	AC2
Number of Residues	1
Details	binding site for residue SO4 A 302

Chain	Residue
A	TRP167

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site_id	AC3
Number of Residues	6
Details	binding site for residue GSH A 303

Chain	Residue
A	TRP167
D	CYS1
D	TRP4
A	ARG62
A	LYS66
A	GLU163

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site_id	AC4
Number of Residues	3
Details	binding site for residue SO4 C 101

Chain	Residue
A	ASP238
C	ARG12
C	ARG12

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site_id	AC5
Number of Residues	7
Details	binding site for residue SO4 D 101

Chain	Residue
A	VAL76
A	ASN80
A	LYS146
A	LYS146
D	PRO7
D	HIS8
D	HIS8

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCRVYH

Chain	Residue	Details
A	TYR257-HIS263
C	TYR78-HIS84

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:3980466, ECO:0000269|PubMed:7118212

Chain	Residue	Details
A	ASN86

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site_id	SWS_FT_FI2
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000305

Chain	Residue	Details
A	ASN176

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site_id	SWS_FT_FI3
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:3980466

Chain	Residue	Details
A	ASN256

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