4PFN
Crystal structure of Plasmodium vivax SHMT with L-serine Schiff base
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004372 | molecular_function | glycine hydroxymethyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0019264 | biological_process | glycine biosynthetic process from serine |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0035999 | biological_process | tetrahydrofolate interconversion |
| A | 0046653 | biological_process | tetrahydrofolate metabolic process |
| B | 0004372 | molecular_function | glycine hydroxymethyltransferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0019264 | biological_process | glycine biosynthetic process from serine |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0035999 | biological_process | tetrahydrofolate interconversion |
| B | 0046653 | biological_process | tetrahydrofolate metabolic process |
| C | 0004372 | molecular_function | glycine hydroxymethyltransferase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005739 | cellular_component | mitochondrion |
| C | 0019264 | biological_process | glycine biosynthetic process from serine |
| C | 0030170 | molecular_function | pyridoxal phosphate binding |
| C | 0035999 | biological_process | tetrahydrofolate interconversion |
| C | 0046653 | biological_process | tetrahydrofolate metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 503 |
| Chain | Residue |
| A | ASN276 |
| A | LYS277 |
| B | ASN276 |
| B | LYS277 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue CL C 503 |
| Chain | Residue |
| C | ASN276 |
| C | ASN276 |
| C | LYS277 |
| C | LYS277 |
| site_id | AC3 |
| Number of Residues | 20 |
| Details | binding site for Di-peptide PLP A 501 and SER A 502 |
| Chain | Residue |
| A | SER100 |
| A | GLY101 |
| A | SER102 |
| A | HIS129 |
| A | TYR182 |
| A | THR183 |
| A | ASP208 |
| A | HIS211 |
| A | THR234 |
| A | HIS236 |
| A | LYS237 |
| A | ARG371 |
| A | HOH659 |
| A | HOH673 |
| A | HOH711 |
| B | TYR54 |
| B | GLU56 |
| B | TYR64 |
| B | GLY272 |
| A | SER34 |
| site_id | AC4 |
| Number of Residues | 22 |
| Details | binding site for Di-peptide PLP B 501 and SER B 502 |
| Chain | Residue |
| A | TYR54 |
| A | GLU56 |
| A | TYR64 |
| A | GLY272 |
| B | SER34 |
| B | SER100 |
| B | GLY101 |
| B | SER102 |
| B | HIS129 |
| B | TYR182 |
| B | THR183 |
| B | ASP208 |
| B | SER210 |
| B | HIS211 |
| B | THR234 |
| B | HIS236 |
| B | LYS237 |
| B | ARG371 |
| B | HOH618 |
| B | HOH661 |
| B | HOH712 |
| B | HOH731 |
| site_id | AC5 |
| Number of Residues | 22 |
| Details | binding site for Di-peptide PLP C 501 and SER C 502 |
| Chain | Residue |
| C | SER34 |
| C | TYR54 |
| C | GLU56 |
| C | TYR64 |
| C | SER100 |
| C | GLY101 |
| C | SER102 |
| C | HIS129 |
| C | TYR182 |
| C | THR183 |
| C | ASP208 |
| C | SER210 |
| C | HIS211 |
| C | THR234 |
| C | HIS236 |
| C | LYS237 |
| C | GLY271 |
| C | GLY272 |
| C | ARG371 |
| C | HOH615 |
| C | HOH617 |
| C | HOH621 |
