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4PB5

D-threo-3-hydroxyaspartate dehydratase H351A mutant complexed with L-erythro-3-hydroxyaspartate

Functional Information from GO Data
ChainGOidnamespacecontents
A0008721molecular_functionD-serine ammonia-lyase activity
A0016829molecular_functionlyase activity
A0016841molecular_functionammonia-lyase activity
A0030170molecular_functionpyridoxal phosphate binding
A0036088biological_processD-serine catabolic process
B0008721molecular_functionD-serine ammonia-lyase activity
B0016829molecular_functionlyase activity
B0016841molecular_functionammonia-lyase activity
B0030170molecular_functionpyridoxal phosphate binding
B0036088biological_processD-serine catabolic process
Functional Information from PDB Data
site_idAC1
Number of Residues5
Detailsbinding site for residue MG A 402
ChainResidue
ACYS353
ABH2403
AHOH630
AHOH666
AHOH699

site_idAC2
Number of Residues5
Detailsbinding site for residue MG B 402
ChainResidue
BHOH660
BCYS353
BBH2403
BHOH658
BHOH659

site_idAC3
Number of Residues8
Detailsbinding site for residue GOL B 404
ChainResidue
AASP303
AGLN305
AARG307
BARG157
BTHR158
BASP161
BHOH502
BHOH514

site_idAC4
Number of Residues24
Detailsbinding site for residues PLP A 401 and BH2 A 403
ChainResidue
AHIS41
ALYS43
AARG141
AHIS172
ATYR177
AGLY216
ASER217
ATHR218
AARG234
AALA235
AGLY236
AVAL237
AMG402
AHOH559
AHOH612
AHOH630
AHOH644
AHOH666
AHOH667
AHOH699
AHOH710
AHOH739
BASN318
BGLN319

site_idAC5
Number of Residues24
Detailsbinding site for residues PLP B 401 and BH2 B 403
ChainResidue
AASN318
AGLN319
BHIS41
BLYS43
BARG141
BHIS172
BTYR177
BGLY216
BSER217
BTHR218
BARG234
BALA235
BGLY236
BVAL237
BMG402
BHOH554
BHOH596
BHOH611
BHOH620
BHOH655
BHOH658
BHOH659
BHOH660
BHOH662

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: N6-(pyridoxal phosphate)lysine => ECO:0000305
ChainResidueDetails
ALYS43
BLYS43

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PDB entries from 2024-11-06

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