Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005198 | molecular_function | structural molecule activity |
| A | 0007155 | biological_process | cell adhesion |
| A | 0015629 | cellular_component | actin cytoskeleton |
| A | 0045296 | molecular_function | cadherin binding |
| A | 0051015 | molecular_function | actin filament binding |
| B | 0005198 | molecular_function | structural molecule activity |
| B | 0007155 | biological_process | cell adhesion |
| B | 0015629 | cellular_component | actin cytoskeleton |
| B | 0045296 | molecular_function | cadherin binding |
| B | 0051015 | molecular_function | actin filament binding |
| C | 0005198 | molecular_function | structural molecule activity |
| C | 0007155 | biological_process | cell adhesion |
| C | 0015629 | cellular_component | actin cytoskeleton |
| C | 0045296 | molecular_function | cadherin binding |
| C | 0051015 | molecular_function | actin filament binding |
| D | 0005198 | molecular_function | structural molecule activity |
| D | 0007155 | biological_process | cell adhesion |
| D | 0015629 | cellular_component | actin cytoskeleton |
| D | 0045296 | molecular_function | cadherin binding |
| D | 0051015 | molecular_function | actin filament binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue IOD A 301 |
| Chain | Residue |
| A | EDO308 |
| B | THR222 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue IOD A 302 |
| Chain | Residue |
| A | MET183 |
| A | ARG210 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue IOD A 304 |
| Chain | Residue |
| A | LYS214 |
| B | LYS215 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 306 |
| Chain | Residue |
| A | GLN194 |
| A | GLN195 |
| A | ARG203 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 307 |
| Chain | Residue |
| A | ALA226 |
| B | LYS185 |
| C | VAL233 |
| C | ALA234 |
| C | ALA235 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 308 |
| Chain | Residue |
| A | VAL184 |
| A | ASN187 |
| A | IOD301 |
| B | MET219 |
| B | THR222 |
| B | ALA223 |
| B | ASN239 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue PEG A 309 |
| Chain | Residue |
| A | GLY211 |
| B | GLY211 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue IOD B 301 |
| Chain | Residue |
| A | THR222 |
| B | EDO308 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue IOD B 302 |
| Chain | Residue |
| B | MET183 |
| B | ARG210 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue IOD B 304 |
| Chain | Residue |
| A | LYS215 |
| B | LYS214 |
| site_id | AD2 |
| Number of Residues | 1 |
| Details | binding site for residue IOD B 305 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 306 |
| Chain | Residue |
| B | GLN194 |
| B | GLN195 |
| B | ARG203 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 307 |
| Chain | Residue |
| A | VAL184 |
| A | LYS185 |
| B | ALA226 |
| D | VAL233 |
| D | ALA234 |
| D | ALA235 |
| site_id | AD5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 308 |
| Chain | Residue |
| A | MET219 |
| A | THR222 |
| A | ALA223 |
| A | ASN239 |
| B | VAL184 |
| B | ASN187 |
| B | IOD301 |
| site_id | AD6 |
| Number of Residues | 2 |
| Details | binding site for residue IOD C 301 |
| Chain | Residue |
| C | EDO308 |
| D | THR222 |
| site_id | AD7 |
| Number of Residues | 2 |
| Details | binding site for residue IOD C 302 |
| Chain | Residue |
| C | MET183 |
| C | ARG210 |
| site_id | AD8 |
| Number of Residues | 2 |
| Details | binding site for residue IOD C 304 |
| Chain | Residue |
| C | LYS214 |
| D | LYS215 |
| site_id | AD9 |
| Number of Residues | 1 |
| Details | binding site for residue IOD C 305 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 306 |
| Chain | Residue |
| C | GLN194 |
| C | GLN195 |
| C | ARG203 |
| site_id | AE2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 307 |
| Chain | Residue |
| A | VAL233 |
| A | ALA234 |
| A | ALA235 |
| C | ALA226 |
| D | VAL184 |
| D | LYS185 |
| site_id | AE3 |
| Number of Residues | 7 |
| Details | binding site for residue EDO C 308 |
| Chain | Residue |
| C | VAL184 |
| C | IOD301 |
| D | MET219 |
| D | THR222 |
| D | ALA223 |
| D | ASN239 |
| D | HOH401 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue PEG C 309 |
| Chain | Residue |
| C | GLY211 |
| C | LYS215 |
| D | GLY211 |
| D | LYS215 |
| site_id | AE5 |
| Number of Residues | 2 |
| Details | binding site for residue IOD D 301 |
| Chain | Residue |
| C | THR222 |
| D | EDO308 |
| site_id | AE6 |
| Number of Residues | 2 |
| Details | binding site for residue IOD D 302 |
| Chain | Residue |
| D | MET183 |
| D | ARG210 |
| site_id | AE7 |
| Number of Residues | 2 |
| Details | binding site for residue IOD D 304 |
| Chain | Residue |
| C | LYS215 |
| D | LYS214 |
| site_id | AE8 |
| Number of Residues | 1 |
| Details | binding site for residue IOD D 305 |
| site_id | AE9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO D 306 |
| Chain | Residue |
| D | GLN194 |
| D | GLN195 |
| D | ARG203 |
| site_id | AF1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 307 |
| Chain | Residue |
| B | VAL233 |
| B | ALA234 |
| B | ALA235 |
| C | LYS185 |
| D | ALA226 |
| site_id | AF2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO D 308 |
| Chain | Residue |
| C | MET219 |
| C | THR222 |
| C | ALA223 |
| C | ASN239 |
| D | VAL184 |
| D | IOD301 |
Functional Information from PROSITE/UniProt
| site_id | PS00663 |
| Number of Residues | 21 |
| Details | VINCULIN_1 Vinculin family talin-binding region signature. KeFgkeMvkLnyvaarRQQEL |
| Chain | Residue | Details |
| A | LYS177-LEU197 | |
