4P93

Structure of Dienelactone Hydrolase at 1.85 A resolution crystallised in the C2 space group

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008806	molecular_function	carboxymethylenebutenolidase activity
A	0009056	biological_process	catabolic process
A	0016787	molecular_function	hydrolase activity
A	0052689	molecular_function	carboxylic ester hydrolase activity
B	0008806	molecular_function	carboxymethylenebutenolidase activity
B	0009056	biological_process	catabolic process
B	0016787	molecular_function	hydrolase activity
B	0052689	molecular_function	carboxylic ester hydrolase activity

Functional Information from PROSITE/UniProt

site_id	PS00061
Number of Residues	29
Details	ADH_SHORT Short-chain dehydrogenases/reductases family signature. DleaairyarHqpYSNGKVGLvGYSlGGA

Chain	Residue	Details
A	ASP99-ALA127

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	ACT_SITE: ACT_SITE => ECO:0000269|PubMed:3221394

Chain	Residue	Details
A	SER123
A	ASP171
A	HIS202
B	SER123
B	ASP171
B	HIS202

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	7
Details	M-CSA 492

Chain	Residue	Details
A	GLU36	proton shuttle (general acid/base)
A	ILE37	electrostatic stabiliser
A	TYR85	electrostatic stabiliser
A	SER123	electrostatic stabiliser
A	LEU124	electrostatic stabiliser
A	ASP171	electrostatic stabiliser
A	HIS202	electrostatic stabiliser

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site_id	MCSA2
Number of Residues	7
Details	M-CSA 492

Chain	Residue	Details
B	GLU36	proton shuttle (general acid/base)
B	ILE37	electrostatic stabiliser
B	TYR85	electrostatic stabiliser
B	SER123	electrostatic stabiliser
B	LEU124	electrostatic stabiliser
B	ASP171	electrostatic stabiliser
B	HIS202	electrostatic stabiliser

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