Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0006584 | biological_process | catecholamine metabolic process |
| A | 0008171 | molecular_function | O-methyltransferase activity |
| A | 0016206 | molecular_function | catechol O-methyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue K A 300 |
| Chain | Residue |
| A | VAL226 |
| A | ARG227 |
| A | SER229 |
| A | PHE232 |
| A | GLU242 |
| A | HOH425 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | binding site for residue SO4 A 301 |
| Chain | Residue |
| A | GLY113 |
| A | TYR114 |
| A | SER115 |
| A | ASP184 |
| A | HOH495 |
| A | HOH497 |
| A | HOH510 |
| A | HOH587 |
| A | ALA110 |
| A | TYR111 |
| A | CYS112 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | VAL85 | |
| A | SER115 | |
| A | GLU133 | |
| A | ASP184 | |
| Chain | Residue | Details |
| A | GLU107 | |
| A | MET134 | |
| A | SER162 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 5 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLY160 | |
| A | LYS187 | |
| A | ASP212 | |
| A | ASN213 | |
| A | GLU242 | |
| Chain | Residue | Details |
| A | SER259 | |
| A | SER260 | |
| A | SER264 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 915 |
| Chain | Residue | Details |
| A | ASP184 | metal ligand |
| A | LYS187 | proton shuttle (general acid/base) |
| A | ASP212 | metal ligand |
| A | ASN213 | metal ligand |
| A | GLU242 | electrostatic stabiliser |
