4P74
PheRS in complex with compound 3a
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000049 | molecular_function | tRNA binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0004826 | molecular_function | phenylalanine-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006432 | biological_process | phenylalanyl-tRNA aminoacylation |
| A | 0009328 | cellular_component | phenylalanine-tRNA ligase complex |
| B | 0000049 | molecular_function | tRNA binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003723 | molecular_function | RNA binding |
| B | 0004826 | molecular_function | phenylalanine-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006432 | biological_process | phenylalanyl-tRNA aminoacylation |
| B | 0009328 | cellular_component | phenylalanine-tRNA ligase complex |
| C | 0000049 | molecular_function | tRNA binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| C | 0004826 | molecular_function | phenylalanine-tRNA ligase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006432 | biological_process | phenylalanyl-tRNA aminoacylation |
| C | 0043039 | biological_process | tRNA aminoacylation |
| D | 0000049 | molecular_function | tRNA binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| D | 0004826 | molecular_function | phenylalanine-tRNA ligase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006432 | biological_process | phenylalanyl-tRNA aminoacylation |
| D | 0043039 | biological_process | tRNA aminoacylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue 2U9 C 301 |
| Chain | Residue |
| C | LEU64 |
| C | CYS204 |
| C | ALA226 |
| C | GLY228 |
| C | GLY230 |
| C | SER92 |
| C | GLN95 |
| C | MET99 |
| C | GLN129 |
| C | GLU131 |
| C | PHE169 |
| C | PHE171 |
| C | GLY203 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue 2U9 D 301 |
| Chain | Residue |
| D | LEU64 |
| D | SER92 |
| D | GLN95 |
| D | MET99 |
| D | GLN129 |
| D | GLU131 |
| D | PHE169 |
| D | PHE171 |
| D | GLY203 |
| D | CYS204 |
| D | ALA226 |
| D | GLY228 |
| D | MET229 |
| D | GLY230 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 216 |
| Details | Domain: {"description":"tRNA-binding","evidences":[{"source":"HAMAP-Rule","id":"MF_00283","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 152 |
| Details | Domain: {"description":"B5","evidences":[{"source":"HAMAP-Rule","id":"MF_00283","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 186 |
| Details | Domain: {"description":"FDX-ACB","evidences":[{"source":"HAMAP-Rule","id":"MF_00283","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00283","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00281","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
