4P73

PheRS in complex with compound 1a

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0000166	molecular_function	nucleotide binding
A	0000287	molecular_function	magnesium ion binding
A	0003723	molecular_function	RNA binding
A	0004812	molecular_function	aminoacyl-tRNA ligase activity
A	0004826	molecular_function	phenylalanine-tRNA ligase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006412	biological_process	translation
A	0006432	biological_process	phenylalanyl-tRNA aminoacylation
A	0009328	cellular_component	phenylalanine-tRNA ligase complex
A	0016874	molecular_function	ligase activity
A	0046872	molecular_function	metal ion binding
B	0000049	molecular_function	tRNA binding
B	0000166	molecular_function	nucleotide binding
B	0000287	molecular_function	magnesium ion binding
B	0003723	molecular_function	RNA binding
B	0004812	molecular_function	aminoacyl-tRNA ligase activity
B	0004826	molecular_function	phenylalanine-tRNA ligase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0006412	biological_process	translation
B	0006432	biological_process	phenylalanyl-tRNA aminoacylation
B	0009328	cellular_component	phenylalanine-tRNA ligase complex
B	0016874	molecular_function	ligase activity
B	0046872	molecular_function	metal ion binding
C	0000049	molecular_function	tRNA binding
C	0000166	molecular_function	nucleotide binding
C	0000287	molecular_function	magnesium ion binding
C	0004812	molecular_function	aminoacyl-tRNA ligase activity
C	0004826	molecular_function	phenylalanine-tRNA ligase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0006412	biological_process	translation
C	0006432	biological_process	phenylalanyl-tRNA aminoacylation
C	0016874	molecular_function	ligase activity
C	0043039	biological_process	tRNA aminoacylation
C	0046872	molecular_function	metal ion binding
D	0000049	molecular_function	tRNA binding
D	0000166	molecular_function	nucleotide binding
D	0000287	molecular_function	magnesium ion binding
D	0004812	molecular_function	aminoacyl-tRNA ligase activity
D	0004826	molecular_function	phenylalanine-tRNA ligase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0006412	biological_process	translation
D	0006432	biological_process	phenylalanyl-tRNA aminoacylation
D	0016874	molecular_function	ligase activity
D	0043039	biological_process	tRNA aminoacylation
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue GAX C 301

Chain	Residue
C	LEU64
C	CYS204
C	ALA226
C	GLY228
C	SER92
C	GLN95
C	MET99
C	GLU131
C	PHE169
C	PHE171
C	THR172
C	GLY203

---

site_id	AC2
Number of Residues	12
Details	binding site for residue GAX D 301

Chain	Residue
D	LEU64
D	SER92
D	GLN95
D	MET99
D	GLU131
D	PHE169
D	PRO170
D	PHE171
D	GLY203
D	CYS204
D	ALA226
D	GLY228

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	216
Details	Domain: {"description":"tRNA-binding","evidences":[{"source":"HAMAP-Rule","id":"MF_00283","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	152
Details	Domain: {"description":"B5","evidences":[{"source":"HAMAP-Rule","id":"MF_00283","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	186
Details	Domain: {"description":"FDX-ACB","evidences":[{"source":"HAMAP-Rule","id":"MF_00283","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00283","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00281","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---