4P0P
Crystal structure of Human Mus81-Eme1 in complex with 5'-flap DNA, and Mg2+
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0006302 | biological_process | double-strand break repair |
| A | 0006308 | biological_process | DNA catabolic process |
| A | 0008821 | molecular_function | crossover junction DNA endonuclease activity |
| B | 0003677 | molecular_function | DNA binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0006281 | biological_process | DNA repair |
| B | 0048476 | cellular_component | Holliday junction resolvase complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 601 |
| Chain | Residue |
| A | ASP274 |
| A | GLU277 |
| A | ASP307 |
| A | HOH720 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 74 |
| Details | Region: {"description":"Helix-hairpin-helix (2HhH); involved in DNA recognition and bending","evidences":[{"source":"PubMed","id":"24733841","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35290797","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"24733841","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35290797","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24733841","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39015284","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4P0P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9F99","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9F9K","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24733841","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39015284","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4P0P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9F9K","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"39015284","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9F9K","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
