4P0E
YhdE E33A (p212121 space group)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0009117 | biological_process | nucleotide metabolic process |
| A | 0016462 | molecular_function | pyrophosphatase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0030145 | molecular_function | manganese ion binding |
| A | 0036218 | molecular_function | dTTP diphosphatase activity |
| A | 0036221 | molecular_function | UTP diphosphatase activity |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0047429 | molecular_function | nucleoside triphosphate diphosphatase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0009117 | biological_process | nucleotide metabolic process |
| B | 0016462 | molecular_function | pyrophosphatase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0030145 | molecular_function | manganese ion binding |
| B | 0036218 | molecular_function | dTTP diphosphatase activity |
| B | 0036221 | molecular_function | UTP diphosphatase activity |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0047429 | molecular_function | nucleoside triphosphate diphosphatase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue PO4 A 201 |
| Chain | Residue |
| A | SER8 |
| A | GLY9 |
| A | ARG13 |
| A | LYS52 |
| A | ALA69 |
| A | HOH326 |
| A | HOH340 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 202 |
| Chain | Residue |
| A | SO4207 |
| A | HOH301 |
| B | GLN59 |
| B | ASN164 |
| A | GLN59 |
| A | ASN164 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 203 |
| Chain | Residue |
| A | GLN42 |
| A | VAL121 |
| A | SO4204 |
| B | HOH312 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 204 |
| Chain | Residue |
| A | VAL121 |
| A | THR122 |
| A | ASP123 |
| A | ASN164 |
| A | SO4203 |
| A | HOH301 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 205 |
| Chain | Residue |
| A | LEU116 |
| A | ASP117 |
| A | HOH353 |
| A | HOH359 |
| A | HOH362 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 206 |
| Chain | Residue |
| A | VAL28 |
| A | THR29 |
| A | GLY30 |
| A | SO4207 |
| B | VAL28 |
| B | GLY30 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 207 |
| Chain | Residue |
| A | VAL28 |
| A | GLN59 |
| A | SO4202 |
| A | SO4206 |
| B | GLN59 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 208 |
| Chain | Residue |
| A | ARG12 |
| A | LYS146 |
| A | GLY154 |
| A | HOH330 |
| A | HOH334 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 B 201 |
| Chain | Residue |
| B | SER8 |
| B | GLY9 |
| B | SER10 |
| B | ARG13 |
| B | LYS52 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_00528, ECO:0000305|PubMed:24210219 |
| Chain | Residue | Details |
| A | ASP70 | |
| B | ASP70 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | SITE: Important for substrate specificity => ECO:0000255|HAMAP-Rule:MF_00528, ECO:0000305|PubMed:24210219 |
| Chain | Residue | Details |
| A | ARG12 | |
| A | THR71 | |
| A | GLN153 | |
| B | ARG12 | |
| B | THR71 | |
| B | GLN153 |
