4OYA

Human solAC Complexed with (4-Aminofurazan-3-yl)-[3-(1H-benzoimidazol-2-ylmethoxy)phenyl]methanone

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0009190	biological_process	cyclic nucleotide biosynthetic process
A	0035556	biological_process	intracellular signal transduction

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for residue 1VE A 501

Chain	Residue
A	PHE45
A	PHE296
A	PHE336
A	MET337
A	PHE338
A	LYS95
A	ALA97
A	ASP99
A	ALA100
A	LEU102
A	LEU166
A	VAL167
A	ARG176

---

site_id	AC2
Number of Residues	9
Details	binding site for residue GOL A 502

Chain	Residue
A	HIS162
A	THR322
A	LEU325
A	LYS326
A	GLY330
A	GLN331
A	ILE332
A	HOH889
A	HOH1050

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	137
Details	Domain: {"description":"Guanylate cyclase 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00099","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	125
Details	Domain: {"description":"Guanylate cyclase 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00099","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25040695","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24567411","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"24616449","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"4USW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00099","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"24567411","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24616449","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4CLL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OYZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"24567411","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"24616449","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"25040695","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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