4OWE

PtCl6 binding to HEWL

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003796	molecular_function	lysozyme activity
A	0003824	molecular_function	catalytic activity
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005737	cellular_component	cytoplasm
A	0005783	cellular_component	endoplasmic reticulum
A	0005794	cellular_component	Golgi apparatus
A	0016231	molecular_function	beta-N-acetylglucosaminidase activity
A	0016787	molecular_function	hydrolase activity
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0016998	biological_process	cell wall macromolecule catabolic process
A	0031640	biological_process	killing of cells of another organism
A	0042742	biological_process	defense response to bacterium
A	0042802	molecular_function	identical protein binding
A	0050829	biological_process	defense response to Gram-negative bacterium
A	0050830	biological_process	defense response to Gram-positive bacterium
A	0051672	biological_process	obsolete catabolism by organism of cell wall peptidoglycan in other organism

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue CL A 201

Chain	Residue
A	ASN65
A	CL202
A	CL203
A	CL205
A	CL206
A	PT218
A	HOH393

---

site_id	AC2
Number of Residues	5
Details	binding site for residue CL A 202

Chain	Residue
A	CL204
A	CL205
A	PT218
A	CL201
A	CL203

---

site_id	AC3
Number of Residues	6
Details	binding site for residue CL A 203

Chain	Residue
A	PRO79
A	CL201
A	CL202
A	CL204
A	CL206
A	PT218

---

site_id	AC4
Number of Residues	6
Details	binding site for residue CL A 204

Chain	Residue
A	LYS1
A	CL202
A	CL203
A	CL205
A	CL206
A	PT218

---

site_id	AC5
Number of Residues	6
Details	binding site for residue CL A 205

Chain	Residue
A	ASN65
A	CL201
A	CL202
A	CL204
A	CL206
A	PT218

---

site_id	AC6
Number of Residues	8
Details	binding site for residue CL A 206

Chain	Residue
A	LYS1
A	GLN41
A	ASN65
A	CL201
A	CL203
A	CL204
A	CL205
A	PT218

---

site_id	AC7
Number of Residues	8
Details	binding site for residue CL A 207

Chain	Residue
A	ALA10
A	ALA11
A	ARG14
A	CL208
A	CL209
A	CL209
A	PT219
A	PT219

---

site_id	AC8
Number of Residues	7
Details	binding site for residue CL A 208

Chain	Residue
A	ARG14
A	CL207
A	CL209
A	CL209
A	CL213
A	PT219
A	PT219

---

site_id	AC9
Number of Residues	8
Details	binding site for residue CL A 209

Chain	Residue
A	GLU7
A	ARG14
A	CL207
A	CL207
A	CL208
A	CL208
A	PT219
A	PT219

---

site_id	AD1
Number of Residues	2
Details	binding site for residue CL A 210

Chain	Residue
A	TYR23
A	ASN113

---

site_id	AD2
Number of Residues	3
Details	binding site for residue CL A 211

Chain	Residue
A	SER24
A	GLY26
A	GLN121

---

site_id	AD3
Number of Residues	5
Details	binding site for residue CL A 212

Chain	Residue
A	ASN65
A	GLY67
A	ARG68
A	THR69
A	ACT223

---

site_id	AD4
Number of Residues	4
Details	binding site for residue CL A 213

Chain	Residue
A	ARG14
A	HIS15
A	CL208
A	CL214

---

site_id	AD5
Number of Residues	2
Details	binding site for residue CL A 214

Chain	Residue
A	ILE88
A	CL213

---

site_id	AD6
Number of Residues	2
Details	binding site for residue CL A 215

Chain	Residue
A	ARG73
A	ASN74

---

site_id	AD7
Number of Residues	2
Details	binding site for residue CL A 216

Chain	Residue
A	ACT221
A	HOH303

---

site_id	AD8
Number of Residues	2
Details	binding site for residue CL A 217

Chain	Residue
A	LYS33
A	PHE38

---

site_id	AD9
Number of Residues	6
Details	binding site for residue PT A 218

Chain	Residue
A	CL201
A	CL202
A	CL203
A	CL204
A	CL205
A	CL206

---

site_id	AE1
Number of Residues	6
Details	binding site for residue PT A 219

Chain	Residue
A	CL207
A	CL207
A	CL208
A	CL208
A	CL209
A	CL209

---

site_id	AE2
Number of Residues	6
Details	binding site for residue NA A 220

Chain	Residue
A	HOH370
A	HOH381
A	SER60
A	CYS64
A	SER72
A	ARG73

---

site_id	AE3
Number of Residues	5
Details	binding site for residue ACT A 221

Chain	Residue
A	ASP48
A	SER50
A	ASN59
A	ARG61
A	CL216

---

site_id	AE4
Number of Residues	6
Details	binding site for residue ACT A 222

Chain	Residue
A	ALA10
A	LYS13
A	ARG14
A	ARG128
A	LEU129
A	HOH306

---

site_id	AE5
Number of Residues	9
Details	binding site for residue ACT A 223

Chain	Residue
A	THR69
A	PRO70
A	GLY71
A	SER72
A	CL212
A	HOH318
A	HOH325
A	HOH325
A	HOH355

---

Functional Information from PROSITE/UniProt

site_id	PS00128
Number of Residues	19
Details	GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. CnipCsaLlssDItasvnC

Chain	Residue	Details
A	CYS76-CYS94

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	128
Details	Domain: {"description":"C-type lysozyme","evidences":[{"source":"PROSITE-ProRule","id":"PRU00680","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	6
Details	M-CSA 203

Chain	Residue	Details
A	GLU35	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
A	ASN46
A	ASP48
A	SER50
A	ASP52	covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction
A	ASN59

---