4OWA
Carboplatin binding to HEWL under sodium iodide crystallisation conditions
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003796 | molecular_function | lysozyme activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0016231 | molecular_function | beta-N-acetylglucosaminidase activity |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0016998 | biological_process | cell wall macromolecule catabolic process |
| A | 0031640 | biological_process | killing of cells of another organism |
| A | 0042742 | biological_process | defense response to bacterium |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0050829 | biological_process | defense response to Gram-negative bacterium |
| A | 0050830 | biological_process | defense response to Gram-positive bacterium |
| A | 0051672 | biological_process | obsolete catabolism by organism of cell wall peptidoglycan in other organism |
| B | 0003796 | molecular_function | lysozyme activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005615 | cellular_component | extracellular space |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005783 | cellular_component | endoplasmic reticulum |
| B | 0016231 | molecular_function | beta-N-acetylglucosaminidase activity |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0016998 | biological_process | cell wall macromolecule catabolic process |
| B | 0031640 | biological_process | killing of cells of another organism |
| B | 0042742 | biological_process | defense response to bacterium |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0050829 | biological_process | defense response to Gram-negative bacterium |
| B | 0050830 | biological_process | defense response to Gram-positive bacterium |
| B | 0051672 | biological_process | obsolete catabolism by organism of cell wall peptidoglycan in other organism |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue IOD A 204 |
| Chain | Residue |
| A | SER24 |
| A | GLY26 |
| A | GLN121 |
| A | ILE124 |
| B | GLN41 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | binding site for residue IOD A 205 |
| Chain | Residue |
| A | ASN74 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue IOD A 206 |
| Chain | Residue |
| A | ARG112 |
| A | LYS116 |
| B | PRO79 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue IOD A 208 |
| Chain | Residue |
| A | ASN106 |
| A | QPT220 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue IOD A 209 |
| Chain | Residue |
| A | ASN106 |
| A | QPT220 |
| B | IOD204 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | binding site for residue IOD A 210 |
| Chain | Residue |
| A | ARG112 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue IOD A 211 |
| Chain | Residue |
| A | ASP119 |
| A | GLN121 |
| B | ASN39 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue IOD A 212 |
| Chain | Residue |
| A | HIS15 |
| A | QPT221 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue IOD A 213 |
| Chain | Residue |
| A | HIS15 |
| A | QPT221 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue IOD A 214 |
| Chain | Residue |
| A | TYR23 |
| B | ARG45 |
| site_id | AD2 |
| Number of Residues | 1 |
| Details | binding site for residue IOD A 215 |
| Chain | Residue |
| A | ASN103 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue IOD A 216 |
| Chain | Residue |
| A | ASP18 |
| B | GLN41 |
| site_id | AD4 |
| Number of Residues | 2 |
| Details | binding site for residue IOD A 219 |
| Chain | Residue |
| A | ASP87 |
| A | ILE88 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue QPT A 220 |
| Chain | Residue |
| A | IOD208 |
| A | IOD209 |
| B | IOD204 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue QPT A 221 |
| Chain | Residue |
| A | HIS15 |
| A | LYS96 |
| A | IOD212 |
| A | IOD213 |
| site_id | AD7 |
| Number of Residues | 2 |
| Details | binding site for residue DMS A 222 |
| Chain | Residue |
| A | TRP62 |
| A | ARG73 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 223 |
| Chain | Residue |
| A | ARG5 |
| A | TRP123 |
| A | ARG125 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 224 |
| Chain | Residue |
| A | GLN57 |
| A | ILE58 |
| A | ASN59 |
| A | TRP63 |
| A | ILE98 |
| A | TRP108 |
| site_id | AE1 |
| Number of Residues | 1 |
| Details | binding site for residue IOD B 201 |
| Chain | Residue |
| B | ARG61 |
| site_id | AE2 |
| Number of Residues | 1 |
| Details | binding site for residue IOD B 202 |
| Chain | Residue |
| B | HOH362 |
| site_id | AE3 |
| Number of Residues | 1 |
| Details | binding site for residue IOD B 203 |
| Chain | Residue |
| B | ASN113 |
| site_id | AE4 |
| Number of Residues | 2 |
| Details | binding site for residue IOD B 204 |
| Chain | Residue |
| A | IOD209 |
| A | QPT220 |
| site_id | AE5 |
| Number of Residues | 1 |
| Details | binding site for residue IOD B 207 |
| Chain | Residue |
| A | SER81 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue IOD B 208 |
| Chain | Residue |
| B | HIS15 |
| B | ASN93 |
| B | IOD212 |
| B | QPT214 |
| site_id | AE7 |
| Number of Residues | 3 |
| Details | binding site for residue IOD B 209 |
| Chain | Residue |
| B | HIS15 |
| B | IOD212 |
| B | QPT214 |
| site_id | AE8 |
| Number of Residues | 1 |
| Details | binding site for residue IOD B 210 |
| Chain | Residue |
| B | ASN37 |
| site_id | AE9 |
| Number of Residues | 1 |
| Details | binding site for residue IOD B 211 |
| Chain | Residue |
| B | HOH333 |
| site_id | AF1 |
| Number of Residues | 3 |
| Details | binding site for residue IOD B 212 |
| Chain | Residue |
| B | IOD208 |
| B | IOD209 |
| B | QPT214 |
| site_id | AF2 |
| Number of Residues | 4 |
| Details | binding site for residue QPT B 214 |
| Chain | Residue |
| B | HIS15 |
| B | IOD208 |
| B | IOD209 |
| B | IOD212 |
| site_id | AF3 |
| Number of Residues | 3 |
| Details | binding site for residue DMS B 215 |
| Chain | Residue |
| B | ARG5 |
| B | ALA122 |
| B | TRP123 |
| site_id | AF4 |
| Number of Residues | 6 |
| Details | binding site for residue DMS B 216 |
| Chain | Residue |
| B | GLN57 |
| B | ILE58 |
| B | ASN59 |
| B | TRP63 |
| B | ALA107 |
| B | TRP108 |
| site_id | AF5 |
| Number of Residues | 6 |
| Details | binding site for residue DMS B 217 |
| Chain | Residue |
| A | THR43 |
| A | ARG45 |
| A | ARG68 |
| B | GLY22 |
| B | TYR23 |
| B | HOH356 |
| site_id | AF6 |
| Number of Residues | 2 |
| Details | binding site for residue ACT B 218 |
| Chain | Residue |
| B | THR47 |
| B | ASP48 |
Functional Information from PROSITE/UniProt
| site_id | PS00128 |
| Number of Residues | 19 |
| Details | GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. CnipCsaLlssDItasvnC |
| Chain | Residue | Details |
| A | CYS76-CYS94 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: |
| Chain | Residue | Details |
| A | GLU35 | |
| A | ASP52 | |
| B | GLU35 | |
| B | ASP52 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ASP101 | |
| B | ASP101 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 6 |
| Details | M-CSA 203 |
| Chain | Residue | Details |
| A | GLU35 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | ASN46 | |
| A | ASP48 | |
| A | SER50 | |
| A | ASP52 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction |
| A | ASN59 |
| site_id | MCSA2 |
| Number of Residues | 6 |
| Details | M-CSA 203 |
| Chain | Residue | Details |
| B | GLU35 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| B | ASN46 | |
| B | ASP48 | |
| B | SER50 | |
| B | ASP52 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction |
| B | ASN59 |
