Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003852 | molecular_function | 2-isopropylmalate synthase activity |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| A | 0009098 | biological_process | L-leucine biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0019752 | biological_process | carboxylic acid metabolic process |
| A | 0043436 | biological_process | oxoacid metabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0046912 | molecular_function | acyltransferase activity, acyl groups converted into alkyl on transfer |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 401 |
| Chain | Residue |
| A | ASP15 |
| A | HIS207 |
| A | HIS209 |
| A | VPM402 |
| A | HOH514 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE VPM A 402 |
| Chain | Residue |
| A | PRO176 |
| A | THR178 |
| A | HIS207 |
| A | HIS209 |
| A | ZN401 |
| A | HOH514 |
| A | HOH568 |
| A | HOH622 |
| A | ARG14 |
| A | ASP15 |
| A | GLN18 |
| A | GLU146 |
Functional Information from PROSITE/UniProt
| site_id | PS00815 |
| Number of Residues | 17 |
| Details | AIPM_HOMOCIT_SYNTH_1 Alpha-isopropylmalate and homocitrate synthases signature 1. LRDGnQalkrPwtideK |
| Chain | Residue | Details |
| A | LEU13-LYS29 | |
| site_id | PS00816 |
| Number of Residues | 14 |
| Details | AIPM_HOMOCIT_SYNTH_2 Alpha-isopropylmalate and homocitrate synthases signature 2. IsiHtHNDlGmAtA |
| Chain | Residue | Details |
| A | ILE204-ALA217 | |
