Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0016491 | molecular_function | oxidoreductase activity |
B | 0004503 | molecular_function | tyrosinase activity |
B | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CU1 A 401 |
Chain | Residue |
A | HIS57 |
A | CYS80 |
A | HIS82 |
A | HIS91 |
A | HOH549 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CU1 A 402 |
Chain | Residue |
A | HIS283 |
A | HOH549 |
A | HIS251 |
A | HIS255 |
A | PHE279 |
A | HIS282 |
site_id | AC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE NA A 403 |
Chain | Residue |
A | GLY55 |
A | ILE56 |
A | GLY58 |
A | PRO60 |
A | HOH547 |
A | HOH548 |
site_id | AC4 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE TRS A 404 |
Chain | Residue |
A | HIS373 |
A | ARG376 |
A | ARG377 |
site_id | AC5 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE TEW A 405 |
Chain | Residue |
A | THR114 |
A | VAL115 |
A | HIS116 |
A | LYS117 |
A | LYS118 |
A | LYS118 |
A | GLU119 |
A | HOH530 |
A | HOH530 |
A | HOH538 |
site_id | AC6 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CU1 B 601 |
Chain | Residue |
B | HIS57 |
B | CYS80 |
B | HIS82 |
B | HIS91 |
B | HOH780 |
site_id | AC7 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CU1 B 602 |
Chain | Residue |
B | HIS251 |
B | HIS255 |
B | PHE279 |
B | HIS283 |
B | HOH780 |
site_id | AC8 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE NA B 603 |
Chain | Residue |
B | GLY55 |
B | ILE56 |
B | GLY58 |
B | PRO60 |
B | HOH725 |
B | HOH734 |
site_id | AC9 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE NA B 604 |
Chain | Residue |
B | GLU231 |
B | ASN235 |
B | GLY237 |
site_id | BC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE NA B 605 |
Chain | Residue |
B | PRO9 |
B | GLU99 |
B | LEU348 |
B | TYR350 |
site_id | BC2 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE TRS B 606 |
Chain | Residue |
B | HIS373 |
B | ARG377 |
B | TRS608 |
site_id | BC3 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE TRS B 607 |
site_id | BC4 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE TRS B 608 |
Chain | Residue |
B | TRS606 |
B | HOH778 |
site_id | BC5 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE TEW B 609 |
Chain | Residue |
B | VAL115 |
B | VAL115 |
B | HIS116 |
B | HIS116 |
B | LYS117 |
B | LYS117 |
B | LYS118 |
B | LYS118 |
B | HOH703 |
B | HOH703 |
B | HOH707 |
B | HOH707 |
B | HOH750 |
B | HOH750 |
Functional Information from PROSITE/UniProt
site_id | PS00497 |
Number of Residues | 18 |
Details | TYROSINASE_1 Tyrosinase CuA-binding region signature. Hsqvl.FPtWHRvyVsiyE |
Chain | Residue | Details |
A | HIS82-GLU99 | |
B | HIS82-GLU99 | |
site_id | PS00498 |
Number of Residues | 12 |
Details | TYROSINASE_2 Tyrosinase and hemocyanins CuB-binding region signature. DPiFWlhHsnvD |
Chain | Residue | Details |
A | ASP276-ASP287 | |
B | ASP276-ASP287 | |