Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004032 | molecular_function | aldose reductase (NADPH) activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0009274 | cellular_component | peptidoglycan-based cell wall |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE MLI A 301 |
| Chain | Residue |
| A | PHE90 |
| A | HOH431 |
| A | HOH607 |
| A | HOH648 |
| A | GLN133 |
| A | LEU197 |
| A | LEU203 |
| A | ALA220 |
| A | ARG243 |
| A | ASN247 |
| A | HOH409 |
| A | HOH428 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE MLI A 302 |
| Chain | Residue |
| A | ALA29 |
| A | TYR57 |
| A | HIS115 |
| A | TYR194 |
| A | CYS195 |
| A | ARG237 |
| A | ARG273 |
| A | HOH408 |
| A | HOH425 |
| A | HOH455 |
| A | HOH503 |
| A | HOH542 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 303 |
| Chain | Residue |
| A | CYS195 |
| A | LEU197 |
| A | LEU199 |
Functional Information from PROSITE/UniProt
| site_id | PS00062 |
| Number of Residues | 18 |
| Details | ALDOKETO_REDUCTASE_2 Aldo/keto reductase family signature 2. MiqsrgeghARSIGVSNF |
| Chain | Residue | Details |
| A | MET131-PHE148 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"P80874","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"A0QV09","evidenceCode":"ECO:0000250"}]} |
