Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 301 |
| Chain | Residue |
| A | LYS61 |
| A | HIS100 |
| A | THR177 |
| A | LYS179 |
| A | MET180 |
| A | HOH546 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 302 |
| Chain | Residue |
| A | ARG206 |
| A | HOH538 |
| A | SER164 |
| A | HIS165 |
| A | ARG166 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 303 |
| Chain | Residue |
| A | ARG35 |
| A | HIS37 |
| A | ARG37 |
| A | TYR60 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT A 304 |
| Chain | Residue |
| A | PRO60 |
| A | LEU88 |
| A | THR97 |
| A | GLU175 |
| A | HOH403 |
| A | HOH418 |
| A | HOH442 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 101 |
| Chain | Residue |
| A | HIS165 |
| A | GLN169 |
| A | VAL176 |
| A | THR177 |
| A | THR178 |
| B | ARG12 |
| site_id | AC6 |
| Number of Residues | 34 |
| Details | BINDING SITE FOR CHAIN B OF BICYCLIC PEPTIDE UK607 (BICYCLIC) |
| Chain | Residue |
| A | GLY19 |
| A | GLU20 |
| A | PHE21 |
| A | ASN26 |
| A | ARG35 |
| A | VAL41 |
| A | HIS57 |
| A | CYS58 |
| A | ASP60 |
| A | TYR60 |
| A | TYR64 |
| A | HIS99 |
| A | GLN169 |
| A | SER174 |
| A | ASP189 |
| A | SER190 |
| A | CYS191 |
| A | GLN192 |
| A | GLY193 |
| A | SER195 |
| A | SER214 |
| A | TRP215 |
| A | GLY218 |
| A | GLY226 |
| A | HOH464 |
| A | HOH506 |
| B | GOL101 |
| B | HOH201 |
| B | HOH202 |
| B | HOH203 |
| B | HOH204 |
| B | HOH205 |
| B | HOH206 |
| B | HOH207 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. ISATHC |
| Chain | Residue | Details |
| A | ILE53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPLV |
| Chain | Residue | Details |
| A | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | HIS57 | |
| A | ASP102 | |
| A | SER195 | |
| Chain | Residue | Details |
| A | SER146 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine |
| Chain | Residue | Details |
| A | GLN145 | |
