4ORU
Three-dimensional structure of the C65A mutant of Human lipocalin-type Prostaglandin D Synthase holo-form second space group
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 32 |
| Details | BINDING SITE FOR RESIDUE PEU A 201 |
| Chain | Residue |
| A | ASN51 |
| A | SER133 |
| A | ASP142 |
| A | PHE143 |
| A | MET145 |
| A | THR147 |
| A | TYR149 |
| A | HOH314 |
| B | ASN51 |
| B | LEU55 |
| B | LYS59 |
| A | SER52 |
| B | LEU62 |
| B | MET64 |
| B | SER81 |
| B | PHE83 |
| B | MET94 |
| B | TYR107 |
| B | TRP112 |
| B | SER133 |
| B | ASP142 |
| B | MET145 |
| A | LEU55 |
| B | TYR149 |
| B | HOH210 |
| B | HOH224 |
| A | LYS59 |
| A | LEU62 |
| A | SER81 |
| A | PHE83 |
| A | MET94 |
| A | TYR116 |
Functional Information from PROSITE/UniProt
| site_id | PS00213 |
| Number of Residues | 14 |
| Details | LIPOCALIN Lipocalin signature. NFQqdKFLGRWFSA |
| Chain | Residue | Details |
| A | ASN33-ALA46 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"20667974","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"O-linked (GalNAc...) serine","evidences":[{"source":"PubMed","id":"23234360","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) (complex) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19838169","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8336134","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) (complex) asparagine","evidences":[{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19139490","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19838169","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22171320","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8336134","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
