4OPL
Constructing tailored isoprenoid products by structure-guided modification of geranylgeranyl reductase.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006650 | biological_process | glycerophospholipid metabolic process |
| A | 0008654 | biological_process | phospholipid biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016628 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE FDA A 501 |
| Chain | Residue |
| A | ILE11 |
| A | PRO46 |
| A | CYS47 |
| A | GLY48 |
| A | ASP49 |
| A | ALA50 |
| A | THR120 |
| A | ALA122 |
| A | ALA156 |
| A | THR157 |
| A | GLY158 |
| A | GLY12 |
| A | SER162 |
| A | ALA185 |
| A | ALA267 |
| A | VAL269 |
| A | GLY287 |
| A | ASP288 |
| A | VAL293 |
| A | GLY299 |
| A | GLY300 |
| A | LYS301 |
| A | GLY14 |
| A | PHE15 |
| A | ALA16 |
| A | ASP35 |
| A | SER36 |
| A | LYS37 |
| A | LYS45 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:21515284, ECO:0000269|PubMed:24954619, ECO:0007744|PDB:3ATQ, ECO:0007744|PDB:4OPC |
| Chain | Residue | Details |
| A | PHE15 | |
| A | ASP35 | |
| A | LYS45 | |
| A | ALA122 | |
| A | ASP288 | |
| A | GLY300 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:24954619, ECO:0007744|PDB:4OPC |
| Chain | Residue | Details |
| A | HIS55 | |
| A | HIS297 | |
| A | TYR340 |
