4OPA

X-ray structure of H6N6-NS1 delta(80-84) mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0005515	molecular_function	protein binding
A	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
A	0030430	cellular_component	host cell cytoplasm
A	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
A	0039524	biological_process	symbiont-mediated suppression of host mRNA processing
A	0039540	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of RIG-I activity
A	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
A	0039657	biological_process	symbiont-mediated suppression of host gene expression
A	0042025	cellular_component	host cell nucleus
A	0052031	biological_process	symbiont-mediated perturbation of host defense response
A	0052170	biological_process	symbiont-mediated suppression of host innate immune response
B	0003723	molecular_function	RNA binding
B	0005515	molecular_function	protein binding
B	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
B	0030430	cellular_component	host cell cytoplasm
B	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
B	0039524	biological_process	symbiont-mediated suppression of host mRNA processing
B	0039540	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of RIG-I activity
B	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
B	0039657	biological_process	symbiont-mediated suppression of host gene expression
B	0042025	cellular_component	host cell nucleus
B	0052031	biological_process	symbiont-mediated perturbation of host defense response
B	0052170	biological_process	symbiont-mediated suppression of host innate immune response

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Motif: {"description":"Nuclear localization signal","evidences":[{"source":"HAMAP-Rule","id":"MF_04066","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	18
Details	Motif: {"description":"Nuclear export signal","evidences":[{"source":"HAMAP-Rule","id":"MF_04066","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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