Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0042820 | biological_process | vitamin B6 catabolic process |
| A | 0070403 | molecular_function | NAD+ binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0006631 | biological_process | fatty acid metabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0042820 | biological_process | vitamin B6 catabolic process |
| B | 0070403 | molecular_function | NAD+ binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE BME A 401 |
| Chain | Residue |
| A | GLU277 |
| B | GLN159 |
| B | THR160 |
| B | HOH690 |
| site_id | AC2 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE NAD A 402 |
| Chain | Residue |
| A | ASP32 |
| A | VAL33 |
| A | ALA37 |
| A | ASN86 |
| A | VAL87 |
| A | PRO88 |
| A | GLU89 |
| A | LYS94 |
| A | ASP114 |
| A | THR115 |
| A | SER116 |
| A | TRP138 |
| A | ASN140 |
| A | HOH539 |
| A | HOH542 |
| A | HOH576 |
| A | HOH595 |
| A | HOH731 |
| A | HOH733 |
| A | HOH765 |
| A | HOH865 |
| A | HOH895 |
| A | ILE8 |
| A | GLY11 |
| A | THR12 |
| A | MET13 |
| A | TYR31 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT A 403 |
| Chain | Residue |
| A | SER116 |
| A | GLY117 |
| A | GLY184 |
| A | ASN188 |
| A | VAL244 |
| A | HOH574 |
| A | HOH830 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT A 404 |
| Chain | Residue |
| A | TYR192 |
| A | ALA236 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BME B 401 |
| Chain | Residue |
| B | GLY276 |
| B | GLU277 |
| A | HOH502 |
| site_id | AC6 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE NAD B 402 |
| Chain | Residue |
| B | ILE8 |
| B | GLY11 |
| B | THR12 |
| B | MET13 |
| B | TYR31 |
| B | ASP32 |
| B | VAL33 |
| B | ASN86 |
| B | VAL87 |
| B | PRO88 |
| B | GLU89 |
| B | LYS94 |
| B | VAL97 |
| B | ASP114 |
| B | THR115 |
| B | SER116 |
| B | HIS137 |
| B | TRP138 |
| B | ASN140 |
| B | HOH571 |
| B | HOH572 |
| B | HOH594 |
| B | HOH598 |
| B | HOH604 |
| B | HOH646 |
| B | HOH696 |
| B | HOH718 |
| B | HOH719 |
| B | HOH763 |
| B | HOH767 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT B 403 |
| Chain | Residue |
| B | TYR192 |
| B | ALA236 |
| B | HOH649 |
| B | HOH776 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 404 |
| Chain | Residue |
| A | HOH642 |
| A | HOH810 |
| B | MET1 |
| B | ILE2 |
| B | THR163 |
| B | ASP166 |
| B | LEU167 |
| B | SER170 |
Functional Information from PROSITE/UniProt
| site_id | PS00067 |
| Number of Residues | 26 |
| Details | 3HCDH 3-hydroxyacyl-CoA dehydrogenase signature. DvpGFVeNRvlyALLreavdlVErgV |
| Chain | Residue | Details |
| A | ASP181-VAL206 | |
| site_id | PS00895 |
| Number of Residues | 14 |
| Details | 3_HYDROXYISOBUT_DH 3-hydroxyisobutyrate dehydrogenase signature. IIGLGtMGpgMAaR |
| Chain | Residue | Details |
| A | ILE7-ARG20 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25446130","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Site: {"description":"Important for catalytic activity","evidences":[{"source":"PubMed","id":"25446130","evidenceCode":"ECO:0000305"}]} |
