4OLC
Carbamate kinase from Giardia lamblia thiocarbamoylated by disulfiram on Cys242
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005829 | cellular_component | cytosol |
| A | 0006525 | biological_process | arginine metabolic process |
| A | 0008804 | molecular_function | carbamate kinase activity |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016310 | biological_process | phosphorylation |
| A | 0019546 | biological_process | arginine deiminase pathway |
| B | 0005829 | cellular_component | cytosol |
| B | 0006525 | biological_process | arginine metabolic process |
| B | 0008804 | molecular_function | carbamate kinase activity |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016310 | biological_process | phosphorylation |
| B | 0019546 | biological_process | arginine deiminase pathway |
| C | 0005829 | cellular_component | cytosol |
| C | 0006525 | biological_process | arginine metabolic process |
| C | 0008804 | molecular_function | carbamate kinase activity |
| C | 0016301 | molecular_function | kinase activity |
| C | 0016310 | biological_process | phosphorylation |
| C | 0019546 | biological_process | arginine deiminase pathway |
| D | 0005829 | cellular_component | cytosol |
| D | 0006525 | biological_process | arginine metabolic process |
| D | 0008804 | molecular_function | carbamate kinase activity |
| D | 0016301 | molecular_function | kinase activity |
| D | 0016310 | biological_process | phosphorylation |
| D | 0019546 | biological_process | arginine deiminase pathway |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE CIT A 401 |
| Chain | Residue |
| A | GLY13 |
| A | ASN55 |
| A | GLY56 |
| A | PRO57 |
| A | ARG163 |
| A | LYS216 |
| A | HOH538 |
| A | HOH544 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE DCD A 402 |
| Chain | Residue |
| A | LEU239 |
| A | SER299 |
| A | ASP237 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE DCD B 401 |
| Chain | Residue |
| B | VAL238 |
| B | ASN240 |
| B | CYS242 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE CIT B 402 |
| Chain | Residue |
| B | GLY12 |
| B | GLY13 |
| B | GLY54 |
| B | ASN55 |
| B | GLY56 |
| B | PRO57 |
| B | LYS131 |
| B | ARG163 |
| B | LYS216 |
| B | LYS278 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE CIT C 401 |
| Chain | Residue |
| C | GLY12 |
| C | GLY13 |
| C | GLY54 |
| C | ASN55 |
| C | GLY56 |
| C | PRO57 |
| C | LYS216 |
| C | LYS278 |
| C | HOH2060 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE DCD C 402 |
| Chain | Residue |
| C | ASP237 |
| C | LEU239 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE CIT D 401 |
| Chain | Residue |
| D | GLY12 |
| D | GLY13 |
| D | GLY54 |
| D | ASN55 |
| D | GLY56 |
| D | PRO57 |
| D | LYS131 |
| D | LYS216 |
| D | LYS278 |
| D | HOH526 |
