4OLC

Carbamate kinase from Giardia lamblia thiocarbamoylated by disulfiram on Cys242

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005829	cellular_component	cytosol
A	0006525	biological_process	arginine metabolic process
A	0008804	molecular_function	carbamate kinase activity
A	0016301	molecular_function	kinase activity
A	0016310	biological_process	phosphorylation
A	0016740	molecular_function	transferase activity
A	0019546	biological_process	arginine deiminase pathway
B	0005829	cellular_component	cytosol
B	0006525	biological_process	arginine metabolic process
B	0008804	molecular_function	carbamate kinase activity
B	0016301	molecular_function	kinase activity
B	0016310	biological_process	phosphorylation
B	0016740	molecular_function	transferase activity
B	0019546	biological_process	arginine deiminase pathway
C	0005829	cellular_component	cytosol
C	0006525	biological_process	arginine metabolic process
C	0008804	molecular_function	carbamate kinase activity
C	0016301	molecular_function	kinase activity
C	0016310	biological_process	phosphorylation
C	0016740	molecular_function	transferase activity
C	0019546	biological_process	arginine deiminase pathway
D	0005829	cellular_component	cytosol
D	0006525	biological_process	arginine metabolic process
D	0008804	molecular_function	carbamate kinase activity
D	0016301	molecular_function	kinase activity
D	0016310	biological_process	phosphorylation
D	0016740	molecular_function	transferase activity
D	0019546	biological_process	arginine deiminase pathway

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE CIT A 401

Chain	Residue
A	GLY13
A	ASN55
A	GLY56
A	PRO57
A	ARG163
A	LYS216
A	HOH538
A	HOH544

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE DCD A 402

Chain	Residue
A	LEU239
A	SER299
A	ASP237

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE DCD B 401

Chain	Residue
B	VAL238
B	ASN240
B	CYS242

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site_id	AC4
Number of Residues	10
Details	BINDING SITE FOR RESIDUE CIT B 402

Chain	Residue
B	GLY12
B	GLY13
B	GLY54
B	ASN55
B	GLY56
B	PRO57
B	LYS131
B	ARG163
B	LYS216
B	LYS278

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site_id	AC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE CIT C 401

Chain	Residue
C	GLY12
C	GLY13
C	GLY54
C	ASN55
C	GLY56
C	PRO57
C	LYS216
C	LYS278
C	HOH2060

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site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE DCD C 402

Chain	Residue
C	ASP237
C	LEU239

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site_id	AC7
Number of Residues	10
Details	BINDING SITE FOR RESIDUE CIT D 401

Chain	Residue
D	GLY12
D	GLY13
D	GLY54
D	ASN55
D	GLY56
D	PRO57
D	LYS131
D	LYS216
D	LYS278
D	HOH526

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