4OKM
Selinadiene Synthase apo and in complex with diphosphate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0010333 | molecular_function | terpene synthase activity |
| A | 0016114 | biological_process | terpenoid biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0010333 | molecular_function | terpene synthase activity |
| B | 0016114 | biological_process | terpenoid biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0010333 | molecular_function | terpene synthase activity |
| C | 0016114 | biological_process | terpenoid biosynthetic process |
| C | 0016829 | molecular_function | lyase activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0010333 | molecular_function | terpene synthase activity |
| D | 0016114 | biological_process | terpenoid biosynthetic process |
| D | 0016829 | molecular_function | lyase activity |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 901 |
| Chain | Residue |
| A | GLU87 |
| A | MG902 |
| A | PPV904 |
| A | HOH1072 |
| A | HOH1202 |
| A | HOH1204 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG A 902 |
| Chain | Residue |
| A | PPV904 |
| A | HOH1125 |
| A | HOH1191 |
| A | HOH1203 |
| A | ASP82 |
| A | GLU87 |
| A | MG901 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 903 |
| Chain | Residue |
| A | ASN224 |
| A | SER228 |
| A | GLU232 |
| A | PPV904 |
| A | HOH1196 |
| site_id | AC4 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE PPV A 904 |
| Chain | Residue |
| A | PHE79 |
| A | ASP82 |
| A | GLU87 |
| A | ARG178 |
| A | ASN224 |
| A | SER228 |
| A | LYS231 |
| A | GLU232 |
| A | ARG310 |
| A | TYR311 |
| A | MG901 |
| A | MG902 |
| A | MG903 |
| A | HOH1020 |
| A | HOH1072 |
| A | HOH1191 |
| A | HOH1202 |
| A | HOH1203 |
| A | HOH1204 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 901 |
| Chain | Residue |
| B | GLU87 |
| B | MG902 |
| B | PPV904 |
| B | HOH1213 |
| B | HOH1218 |
| B | HOH1230 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG B 902 |
| Chain | Residue |
| B | ASP82 |
| B | GLU87 |
| B | MG901 |
| B | PPV904 |
| B | HOH1003 |
| B | HOH1017 |
| B | HOH1107 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 903 |
| Chain | Residue |
| B | ASN224 |
| B | SER228 |
| B | GLU232 |
| B | PPV904 |
| B | HOH1236 |
| site_id | AC8 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE PPV B 904 |
| Chain | Residue |
| B | ASP82 |
| B | GLU87 |
| B | ARG178 |
| B | ASN224 |
| B | SER228 |
| B | LYS231 |
| B | GLU232 |
| B | ARG310 |
| B | TYR311 |
| B | MG901 |
| B | MG902 |
| B | MG903 |
| B | HOH1017 |
| B | HOH1047 |
| B | HOH1107 |
| B | HOH1213 |
| B | HOH1218 |
| B | HOH1230 |
| B | HOH1236 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG C 901 |
| Chain | Residue |
| C | ASP82 |
| C | GLU87 |
| C | MG902 |
| C | PPV904 |
| C | HOH1010 |
| C | HOH1186 |
| C | HOH1206 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG C 902 |
| Chain | Residue |
| C | ASP82 |
| C | GLU87 |
| C | MG901 |
| C | PPV904 |
| C | HOH1023 |
| C | HOH1086 |
| C | HOH1205 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG C 903 |
| Chain | Residue |
| C | ASN224 |
| C | SER228 |
| C | GLU232 |
| C | PPV904 |
| C | HOH1202 |
| site_id | BC3 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE PPV C 904 |
| Chain | Residue |
| C | GLU232 |
| C | ARG310 |
| C | TYR311 |
| C | MG901 |
| C | MG902 |
| C | MG903 |
| C | HOH1010 |
| C | HOH1016 |
| C | HOH1086 |
| C | HOH1186 |
| C | HOH1202 |
| C | HOH1205 |
| C | HOH1206 |
| C | ASP82 |
| C | GLU87 |
| C | ARG178 |
| C | ASN224 |
| C | SER228 |
| C | LYS231 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 15 |
| Details | Motif: {"description":"DDXXXE motif","evidences":[{"source":"PubMed","id":"24890698","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 25 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24890698","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4OKM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OKZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24890698","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4OKZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | Site: {"description":"Plays a critical role in the stabilization of intermediate cation","evidences":[{"source":"PubMed","id":"24890698","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | Site: {"description":"Plays a critical role for substrate recognition","evidences":[{"source":"PubMed","id":"24890698","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Site: {"description":"Plays a critical role for abstraction of the pyrophosphate group","evidences":[{"source":"PubMed","id":"24890698","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
