4OH0

Crystal structure of OXA-58 carbapenemase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008658	molecular_function	penicillin binding
A	0008800	molecular_function	beta-lactamase activity
A	0017001	biological_process	antibiotic catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 301

Chain	Residue
A	SER221
A	GLY222
A	ARG263
A	HOH621
A	HOH706

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Functional Information from PROSITE/UniProt

site_id	PS00337
Number of Residues	11
Details	BETA_LACTAMASE_D Beta-lactamase class-D active site. PaSTFKIAnAL

Chain	Residue	Details
A	PRO81-LEU91

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Acyl-ester intermediate","evidences":[{"source":"PIRSR","id":"PIRSR602137-50","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"26459904","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4Y0U","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26459904","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4Y0U","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P13661","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q8RLA6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"N6-carboxylysine","evidences":[{"source":"PIRSR","id":"PIRSR602137-50","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24468777","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26459904","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26701320","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4OH0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4Y0O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4Y0T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4Y0U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5BOH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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