Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051607 | biological_process | defense response to virus |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1201 |
| Chain | Residue |
| A | CYS566 |
| A | CYS569 |
| A | CYS602 |
| A | CYS605 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 1202 |
| Chain | Residue |
| A | HOH1640 |
| A | ASP581 |
| A | ASN606 |
| A | HOH1637 |
| A | HOH1638 |
| A | HOH1639 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG A 1203 |
| Chain | Residue |
| A | ASP17 |
| A | GLU505 |
| A | HOH1643 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 1204 |
| Chain | Residue |
| A | GLN586 |
| A | GLY588 |
| A | GLY590 |
| A | HOH1634 |
| A | HOH1635 |
| A | HOH1636 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SPD A 1205 |
| Chain | Residue |
| A | ALA708 |
| A | LYS711 |
| A | ALA712 |
| A | LEU754 |
| A | ARG757 |
| A | SER758 |
| A | ARG761 |
| A | TRP773 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SPD A 1206 |
| Chain | Residue |
| A | ARG817 |
| A | SER821 |
| A | PRO924 |
| A | SER925 |
| A | ILE926 |
| A | HIS927 |
| A | HOH1378 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 45 |
| Details | Region: {"description":"RuvC-II","evidences":[{"source":"PubMed","id":"24505130","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 148 |
| Details | Region: {"description":"RuvC-III","evidences":[{"source":"PubMed","id":"24505130","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 177 |
| Details | Region: {"description":"PAM-interacting domain (PI)","evidences":[{"source":"PubMed","id":"24505130","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Active site: {"description":"For RuvC-like nuclease domain","evidences":[{"source":"UniProtKB","id":"Q99ZW2","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor for HNH nuclease domain","evidences":[{"source":"PubMed","id":"24505130","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24505130","evidenceCode":"ECO:0000269"}]} |
