Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004478 | molecular_function | methionine adenosyltransferase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006556 | biological_process | S-adenosylmethionine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE SAM A 500 |
| Chain | Residue |
| A | HIS34 |
| A | ASP187 |
| A | LYS189 |
| A | SER255 |
| A | ARG257 |
| A | PHE258 |
| A | ASP266 |
| A | LYS297 |
| A | 3PO501 |
| A | HOH609 |
| A | HOH611 |
| A | PRO35 |
| A | HOH639 |
| A | HOH653 |
| A | HOH656 |
| A | HOH704 |
| A | ALA60 |
| A | GLU75 |
| A | GLN118 |
| A | GLN121 |
| A | ILE122 |
| A | GLY138 |
| A | ASP139 |
| site_id | AC2 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE 3PO A 501 |
| Chain | Residue |
| A | HIS34 |
| A | ASP36 |
| A | ASP139 |
| A | LYS189 |
| A | ARG272 |
| A | LYS273 |
| A | GLY288 |
| A | ALA289 |
| A | LYS293 |
| A | ASP299 |
| A | SAM500 |
| A | MG502 |
| A | MG503 |
| A | HOH679 |
| A | HOH703 |
| A | HOH704 |
| A | HOH742 |
| A | HOH745 |
| A | HOH746 |
| A | HOH839 |
| A | HOH840 |
| A | HOH841 |
| A | HOH842 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 502 |
| Chain | Residue |
| A | ASP36 |
| A | LYS273 |
| A | 3PO501 |
| A | HOH745 |
| A | HOH839 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG A 503 |
| Chain | Residue |
| A | ASP299 |
| A | 3PO501 |
| A | HOH741 |
| A | HOH742 |
| A | HOH840 |
| A | HOH841 |
| A | HOH842 |
Functional Information from PROSITE/UniProt
| site_id | PS00178 |
| Number of Residues | 10 |
| Details | AA_TRNA_LIGASE_I Aminoacyl-transfer RNA synthetases class-I signature. P..SGrFTIGGP |
| Chain | Residue | Details |
| A | PRO254-PRO263 | |
| site_id | PS00376 |
| Number of Residues | 11 |
| Details | ADOMET_SYNTHASE_1 S-adenosylmethionine synthase signature 1. GAGDQGmmfGY |
| Chain | Residue | Details |
| A | GLY136-TYR146 | |
| site_id | PS00377 |
| Number of Residues | 9 |
| Details | ADOMET_SYNTHASE_2 S-adenosylmethionine synthase signature 2. GGGAFSgKD |
| Chain | Residue | Details |
| A | GLY286-ASP294 | |
