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4OD2

Crystal structure of the Fab fragment of an anti-DR5 antibody bound to DR5

Functional Information from GO Data
ChainGOidnamespacecontents
S0045569molecular_functionTRAIL binding
Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YSCQVTH
ChainResidueDetails
ATYR192-HIS198
BTYR202-HIS208

site_idPS00652
Number of Residues41
DetailsTNFR_NGFR_1 TNFR/NGFR family cysteine-rich region signature. Ckygqd.Ysthwndllf.ClrCtr.Cdsgevelsp..Ctttr..NTVC
ChainResidueDetails
SCYS44-CYS84
SCYS84-CYS125

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues40
DetailsRepeat: {"description":"TNFR-Cys 2"}
ChainResidueDetails

245663

PDB entries from 2025-12-03

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