4OBA
Co-crystal structure of MDM2 with Inhibitor Compound 4
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005634 | cellular_component | nucleus |
| A | 0043066 | biological_process | negative regulation of apoptotic process |
| A | 0051726 | biological_process | regulation of cell cycle |
| B | 0005634 | cellular_component | nucleus |
| B | 0043066 | biological_process | negative regulation of apoptotic process |
| B | 0051726 | biological_process | regulation of cell cycle |
| C | 0005634 | cellular_component | nucleus |
| C | 0043066 | biological_process | negative regulation of apoptotic process |
| C | 0051726 | biological_process | regulation of cell cycle |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 2TW A 501 |
| Chain | Residue |
| A | LEU54 |
| B | ARG97 |
| A | GLY58 |
| A | GLN59 |
| A | ILE61 |
| A | MET62 |
| A | VAL93 |
| A | HIS96 |
| A | ILE99 |
| A | TYR100 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 2TW B 501 |
| Chain | Residue |
| B | LEU54 |
| B | GLY58 |
| B | GLN59 |
| B | ILE61 |
| B | MET62 |
| B | VAL93 |
| B | HIS96 |
| B | ILE99 |
| B | TYR100 |
| C | ARG97 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2TW C 501 |
| Chain | Residue |
| A | ARG97 |
| C | LEU54 |
| C | GLY58 |
| C | ILE61 |
| C | VAL93 |
| C | HIS96 |
| C | ILE99 |
| C | HOH620 |
