4O7I
Structural and functional characterization of 3'(2'),5'-bisphosphate nucleotidase1 from Entamoeba histolytica
Replaces: 4GDGFunctional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000103 | biological_process | sulfate assimilation |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004441 | molecular_function | inositol-1,4-bisphosphate 1-phosphatase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006790 | biological_process | sulfur compound metabolic process |
| A | 0008441 | molecular_function | 3'(2'),5'-bisphosphate nucleotidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046854 | biological_process | phosphatidylinositol phosphate biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 401 |
| Chain | Residue |
| A | GLU69 |
| A | ASP118 |
| A | ILE120 |
| A | HOH602 |
| A | HOH603 |
| A | HOH604 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 A 402 |
| Chain | Residue |
| A | SER227 |
| A | LYS230 |
| A | ARG244 |
| A | HOH554 |
| A | HOH605 |
| A | SER198 |
| A | HIS203 |
| A | ASP226 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"P32179","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P32179","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25004978","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"4HXV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4O7I","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25004978","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4HXV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4O7I","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25004978","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4HXV","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
